固有免疫和适应性免疫在变应性鼻炎发病中的作用机制

邱昌余; 崔昕燕; 程雷

doi:10.13201/j.issn.1001-1781.2019.01.007

固有免疫和适应性免疫在变应性鼻炎发病中的作用机制

- 1. 南京医科大学第一附属医院江苏省人民医院耳鼻咽喉科(南京, 210029);
- 2. 南京医科大学国际变态反应研究中心;
- 3. 江苏省临床医学研究院过敏与自身免疫性疾病研究所
基金项目:
国家自然科学基金(No:81600789)

江苏省基础研究计划-自然科学基金(No:BK20161058)

江苏高校优势学科建设工程(No:JX10231801)

详细信息

通讯作者: 程雷,E-mail:chenglei@jsph.org.cn

中图分类号: R765.21

收稿日期: 2018-10-09

Mechanism of innate immunity and adaptive immunity in the development of allergic rhinitis

More Information

Corresponding author: , E-mail: chenglei@jsph.org.cn

Received Date: 09 October 2018

摘要

- 鼻炎 /
- 变应性 /
- 固有免疫 /
- 适应性免疫 /
- Toll样受体
Abstract: The pathogenesis of allergic rhinitis (AR) has not well been clarified, and the imbalance of immune system is its important feature.Interaction between innate and adaptive immune cells and inflammatory mediators secreted by them triggers, maintains and aggravates AR.In this review, Toll-like receptor signaling pathways are used as a bridge to systematically analyze the mechanisms of innate and adaptive immunity in the development of AR.
- rhinitis /
- allergic /
- innate immunity /
- adaptive immunity /
- Toll-like receptor

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