Risk factors for recurrence of benign paroxysmal positional vertigo: a Meta analysis
-
摘要: 目的:应用Meta分析法探讨良性阵发性位置性眩晕(BPPV)行耳石复位后复发的相关危险因素。方法:检索PubMed、Embase、OVID、Springer、Proquest等数据库,筛选BPPV复发危险因素的相关文献,采用Revman 5.3软件对纳入的文献进行Meta分析。结果:最终纳入的文献共15篇,累计样本量共4 477例。Meta分析结果表明:伴有高脂血症较不伴有高脂血症患者(OR=1.74,95%CI 1.14~2.65,P=0.01),伴有梅尼埃病较不伴有梅尼埃病患者(OR=4.57,95%CI 2.78~7.52,P<0.01)BPPV耳石复位后复发率增加,差异有统计学意义;伴有糖尿病较不伴有糖尿病患者(OR=1.14,95%CI 0.84~1.54,P>0.05)和伴有偏头痛较不伴有偏头痛患者(OR=0.99,95%CI 0.66~1.47,P>0.05)BPPV耳石复位后复发差异无统计学意义。结论:伴有高脂血症、梅尼埃病为BPPV耳石复位后复发的危险因素。
-
关键词:
- 良性阵发性位置性眩晕 /
- 复发 /
- 危险因素
Abstract: Objective: To investigate the risk factors for recurrence after otolith reduction of benign paroxysmal positional vertigo by Meta analysis. Method: The relevant literatures of risk factors for recurrence of BPPV were searched by the database of PubMed, Embase, OVID, Springer, Proquest. Revman 5.3 software was used to perform Meta analysis of the included literature. Result: A total of 15 articles were included in the final analysis and a total of 4 477 cases were included. Meta analysis results showed:the recurrent after otolith reduction of BPPV in patients with the hyperlipidemia and Meniere's disease increased significantly, compared to the patients without the hyperlipidemia and Meniere's disease, difference was statistically significant[OR=1.74, 95%CI(1.14-2.65), P=0.01;OR=4.57, 95%CI(2.78-7.52), P<0.01]. There was no significant difference in the recurrence after otolith reduction of BPPV in patients with diabetes and migraine compared without diabetes and migraine[OR=1.14, 95%CI(0.84-1.54), P>0.05; OR=0.99, 95%CI(0.66-1.47), P>0.05]. Conclusion: Hyperlipidemia and Meniere's disease are risk factors for the recurrence after otolith reduction of BPPV.-
Key words:
- benign paroxysmal positional vertigo /
- recurrence /
- risk factors
-
-
[1] BHATTACHARYYA N, BAUGH R F, ORVIDAS L, et al.Clinical practice guideline:benign paroxysmal positional vertigo[J].Otolaryngol Head Neck Surg, 2008, 139:47-81.
[2] VON BREVERN M, RADTKE A, LEZIUS F, et al.Epidemiologyof benign paroxysmal positional vertigo:apopulation based study[J].J Neurol Neurosurg Psychiatry, 2007, 78:710-715.
[3] HIROKO MONOBE K S T M.The Outcome of the Canalith repositioning procedure for benign paroxysmal positional vertigo:are there any characteristic features of treatment failure cases[J]?Acta Otolaryngol, 2001, 545:38-40.
[4] PÉREZ P, FRANCO V, CUESTA P, et al.Recurrence of benign paroxysmal positional vertigo[J].Otol Neurol, 2012, 33:437-443.
[5] CHOI S J, LEE J B, LIM H J, et al.Clinical features of recurrent or persistent benign paroxysmal positional vertigo[J].Otolaryngol Head Neck Surg, 2012, 147:919-924.
[6] WEBSTER G, SENS P M, SALMITO M C, et al.Hyperinsulinemia and hypoglycemia:risk factors for recurrence of benign paroxysmal positional vertigo[J].Brazilian J Otorhinolaryngol, 2015, 81:347-351.
[7] BALATSOURAS D G, GANELIS P, ASPRIS A, et al.Benign paroxysmal positional vertigo associated with Meniere's disease:epidemiological, pathophysiologic, clinical, and therapeutic aspects[J].Ann Otol Rhinol Laryngol, 2012, 121:682-688.
[8] BABAC S, DJERIC D, PETROVICLAZIC M, et al.Why do treatment failure and recurrences of benign paroxysmal positional vertigo occur[J]?Otol Neurotol, 2014, 35:1105-1110.
[9] LURYI A L, LAWRENCE J, BOJRAB D I, et al.Recurrence in benign paroxysmal positional vertigo:a large, single-institution study[J].Otol Neurotol, 2018, 39:622-627.
[10] DORNHOFFER J L, COLVIN G B.Benign paroxysmal positional vertigo and canalith repositioning:clinical correlations[J].Am J Otol, 2000, 21:230-233.
[11] OGUN O A, JANKY K L, COHN E S, et al.Genderbased comorbidity in benign paroxysmal positional vertigo[J].Plos One, 2014, 9:e105546.
[12] KANSU L, AVCI S, YILMAZ I, et al.Long-term follow-up of patients with posterior canal benign paroxysmal positional vertigo[J].Acta Otolaryngol, 2010, 130:1009-1012.
[13] DE S A, DISPENZA F, SUAREZ H, et al.A multicenter observational study on the role of comorbidities in the recurrent episodes of benign paroxysmal positional vertigo[J].Auris Nasus Larynx, 2014, 41:31-36.
[14] TAN J, DENG Y, ZHANG T, et al.Clinical characteristics and treatment outcomes for benign paroxysmal positional vertigo comorbid with hypertension[J].Acta Otolaryngol, 2017, 137:482-484.
[15] 刘向红, 李广生.良性阵发性位置性眩晕复发临床研究[J].临床耳鼻咽喉头颈外科杂志, 2009, 23(7):304-306.
[16] 田永胜, 王淑珍, 刘颖, 等.特发性良性阵发性位置性眩晕复发特点分析[J].临床耳鼻咽喉头颈外科杂志, 2018, 32(2):118-121.
[17] 吕肖玉, 赵性泉, 陈梅梅, 等.良性阵发性位置性眩晕伴有梅尼埃病的临床特征[J].北京医学, 2017, 39(8):777-779.
[18] 郭向东, 叶放蕾, 李莹, 等.良性阵发性位置性眩晕预后分析[J].中国耳鼻咽喉头颈外科, 2010, 17(6):297-299.
[19] 陈请国, 王兴龙, 毛忠瑶, 等.良性阵发性位置性眩晕的复发影响因素分析[J].中华物理医学与康复杂志, 2015, 37(9):683-685.
[20] 卫旭东.良性阵发性位置性眩晕诊治进展[J].临床耳鼻咽喉头颈外科杂志, 2016, 30(5):345-348.
[21] STEFANO A D, DISPENZA F, SUAREZ H, et al.A multicenter observational study on the role of comorbidities in the recurrent episodes of benign paroxysmal positional vertigo[J].Auris Nasus Larynx, 2014, 41:31-36.
[22] KORKMAZ M, KORKMAZ H.Cases requiring increased number of repositioning maneuvers in benign paroxysmal positional vertigo[J].Brazilian J Otorhinolaryngol, 2016, 82:452-457.
[23] CELIKBILEK A, GENCER Z K, SAYDAM L, et al.Serum uric acid levels correlate with benign paroxysmal positional vertigo[J].Eur J Neurol, 2014, 21:79-85.
[24] 闫亚平, 薄建华.中国人群高脂血症与良性阵发性位置性眩晕复发风险的Meta分析[J].武警医学, 2016, 27(8):803-805.
[25] D'SILVA L J, STAECKER H, LIN J, et al.Otolith dysfunction in persons with both diabetes and benign paroxysmal positional vertigo[J].Otol Neurotol, 2017, 38:379-385.
[26] BALOH R W.Neurotology of migraine[J].J HeadFace Pain, 1997, 37:615-621.
[27] ISHIYAMA A, JACOBSON K M, BALOH R W.Migraine and benign positional vertigo[J].Ann Otol Rhinol Laryngol, 2000, 109:377-380.
[28] HUGHES C A, PROCTOR L.Benign paroxysmal positional vertigo[J].Laryngoscope, 1997, 107:607-613.
[29] GROSS E M, RESS B D, VIIRRE E S, et al.Intractable benign paroxysmal positional vertigo in patients with Meniere's disease[J].Laryngoscope, 2000, 110:655-659.
[30] 张道宫, 樊兆民, 王海波.梅尼埃病的外科治疗[J].临床耳鼻咽喉头颈外科杂志, 2016, 30(1):6-8.
[31] 李斐, 庄建华, 陈瑛, 等.梅尼埃病不同听力分期中颈肌前庭诱发肌源性电位的差异[J].临床耳鼻咽喉头颈外科杂志, 2016, 30(1):9-12.
-
计量
- 文章访问数: 183
- PDF下载数: 114
- 施引文献: 0