Evaluation of curative effect of VNG and VEMP in patients with severe sudden hearing loss
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摘要: 目的:评估重度以上突聋患者的前庭功能情况,探讨前庭功能检查与其疗效的关系。方法:用视频眼震图(VNG)及前庭诱发肌源性电位(VEMP)技术评估79例重度以上突聋患者的前庭功能。根据检查结果分为VNG与VEMP均正常、VNG正常与VEMP异常、VNG异常与VEMP正常及VNG与VEMP均异常4个组。应用SPSS 22.0软件进行统计分析,重度组与极重度组组内、组间2项检查结果与疗效关系比较均采用χ2检验及Fisher检验,以P<0.05为差异有统计学意义。结果:重度组患者(27例)2项检查结果与疗效之间差异有统计学意义(P<0.01),其中VNG与VEMP均正常组有效率为100%,VNG与VEMP均异常组有效率为41.7%;极重度组患者(52例)2项检查结果与疗效之间差异也有统计学意义(P<0.01),其中VNG与VEMP均正常组有效率为76.9%,VNG与VEMP均异常组有效率为34.6%。重度组和极重度组程度与疗效之间差异无统计学意义。结论:VNG及VEMP检查对重度以上突聋患者的疗效评估有一定的价值。2项检查均异常组疗效最差。Abstract: Objective: To evaluate the relationship between vestibular function and curative effect in patients with severe sudden hearing loss.Method: The vestibular function of 79 patients with severe hearing loss was examined by video-nystagmography (VNG) and vestibular evoked myogenic potential (VEMP).Result: There were significant differences between the two test outcomes (P<0.01) in the severe group (27 cases). The effective rate of both VNG and VEMP normal group was 100%, the effective rate that both VNG and VEMP were abnormal was 41.7%. In the profound severe group (52 cases) there was also a significant difference between the two test results and the therapeutic effect (P<0.01). The effective rate of both VNG and VEMP normal group was 76.9%. The effective rate was 34.6% with both VNG and VEMP abnormal. There was no significant difference between hearing loss degree and curative effect.Conclusion: The VNG and VEMP examinations in patients with severe sudden hearing loss are valuable in evaluating the efficacy. Both VNG and VEMP were abnormal with the worst curative effect.
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