72例0~4岁双胎儿童的临床听力学及病因学分析

赵雪雷; 黄丽辉; 王现蕾; 王雪瑶

doi:10.13201/j.issn.1001-1781.2018.13.005

72例0~4岁双胎儿童的临床听力学及病因学分析

- 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科北京市耳鼻咽喉科研究所耳鼻咽喉头颈外科学教育部重点实验室(北京, 100005)
基金项目:
北京市自然科学基金面上项目（No：7172052）

详细信息

通讯作者: 黄丽辉,E-mail:huangpub@126.com

中图分类号: R764.4

收稿日期: 2018-05-21

Analysis of clinical audiology and etiology in 72 twins aged 0-4 years

- Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otolaryngology, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Beijing, 100005, China

More Information

Corresponding author: HUANG Lihui, E-mail: huangpub@126.com

Received Date: 21 May 2018

摘要

摘要: 目的：探讨双胎儿童的临床听力学特点，分析其听力损失高危因素。方法：研究对象为在首都医科大学附属北京同仁医院就诊的72例0~4岁双胎儿童。所有受试者均接受新生儿听力筛查并有明确结果；同时接受声导抗、耳声发射、听性脑干反应、多频稳态诱发电位和小儿行为测听等听力学检测。根据是否具有听力损失高危因素将受试者分为2个组：A组（高危因素组），42例（58.33%）；B组（无高危因素组），30例（41.67%）。对2组受试者的听力筛查结果、听力确诊情况、听力损失程度、听力曲线类型及听力损失高危因素类别进行分析。结果：72例患儿中，男41例，女31例；长子31例，次子41例；年龄3~40个月，中位年龄4.6个月。新生儿听力筛查未通过47例（65.27%），未通过率A组（76.19%）高于B组（50.00%）；确诊听力损失50例（69.44%）， A组（78.57%）高于B组（56.67%）；听力损失程度A组以极重度（43.55%）为主，B组以中度（48.00%）为主，上述均差异有统计学意义。听力曲线类型A组（35.48%）和B组（40.00%）均以平坦型为主，差异无统计学意义。72例患儿中，具有听力损失高危因素42例（58.33%），其中，38.1%伴2种及以上高危因素，61.9%具有1种高危因素。高胆红素血症为主要高危因素（34.92%）。结论：69.44%的双胎儿童确诊听力损失，具有高危因素者听力筛查未通过率较高且听力损失程度更重。58.33%的双胎儿童具有听力损失高危因素，同时伴有多种高危因素者较多，高胆红素血症占首位，临床应予以重视。
- 双胎 /
- 高危因素 /
- 听力筛查 /
- 听力损失
Abstract: Objective: To investigate the clinical audiological characteristics of twins and analyze the risk factors for hearing loss. Method: The subjects were 72 cases, selected from our hospital otological outpatient of 0 to 4 years old twins. All subjects underwent universal newborn hearing screening and had definite results. At the same time, acoustic immittance, auditory brainstem response, auditory steady-state response, pediatric behavior audiometry and other audiological tests were carried out. Subjects were divided into two groups according to whether with high risk factors for hearing loss:42 patients (58.33%) in group A (risk factor group) and 30 patients (41.67%) in group B (no risk factor group). The results of universal newborn hearing screening(UNHS), hearing diagnosis, degree of hearing loss, type of hearing curve and risk factors categories of hearing loss were analyzed for both groups of subjects. Result: In 72 cases, 41 were males and 31 were females. Thirty-one were the first born and 41 were the second born. Age distribution of first visit:3 to 40 months, median age:4.6 months. Forty-seven(65.27%) failed in the UNHS. The failing rate was higher in group A (76.19%) than in group B (50.00%). Fifty(69.44%) were diagnosed with hearing loss. 78.57% of hearing loss was diagnosed in group A, which was higher than that in group B (56.67%). The degree of hearing loss in group A was mainly profound (43.55%) and group B was moderate (48.00%). The differences above all was statistically significant. For the hearing curve type, group A (35.48%) and group B (40.00%) were both mainly flat-type, the difference was not statistically significant. In 72 cases, there were 42 cases (58.33%) with risk factors for hearing loss, of which 38.1% had two or more kinds of risk factors and 61.9% had one kind of risk factor. Hyperbilirubinemia was the major risk factor (34.92%).Conclusion: 69.44% of twins had a confirmed hearing loss. Those with risk factors had higher failing rate of UNHS and more serious hearing loss. 58.33% of twins had risk factors for hearing loss, and individuals with two or more kinds of risk factors were much more. Hyperbilirubinemia takes the first place and should be paid enough attention by clinicians.
- twin /
- risk factors /
- hearing screening /
- hearing loss

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参考文献(13)

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