个性化多元复合声对慢性主观性耳鸣临床疗效的初步分析

罗彬; 熊彬彬; 孙伟; 赵晓明; 刘钊; 刘劲; 林春梅; 彭玥

doi:10.13201/j.issn.1001-1781.2018.11.005

个性化多元复合声对慢性主观性耳鸣临床疗效的初步分析

- 1. 暨南大学附属珠海医院(珠海市人民医院)耳鼻咽喉头颈外科(广东珠海, 519000);
- 2. 听力与聋病中心纽约州立布法罗大学
基金项目:
国家自然科学基金（No：81528005）；珠海市科技计划项目（No：20171009E030055）

详细信息

通讯作者: 熊彬彬,E-mail:xiongbb2015@126.com

中图分类号: R764.45

收稿日期: 2018-04-11

Preliminary analysis of the effects of individualized sound therapy on chronic subjective tinnitus

- 1. Department of Otolaryngology Head and Neck Surgery, Zhuhai Hospital Affiliated with Ji'nan University (Zhuhai People's Hospital), Zhuhai, 519000, China;
- 2. Center for Hearing & Deafness, Department of Communicative Disorders and Science, State University of New York at Buffalo, 3435 Main Street, Buffalo, NY 14214

More Information

Corresponding author: XIONG Binbin, E-mail: xiongbb2015@126.com

Received Date: 11 April 2018

摘要

摘要: 目的：探讨个性化定制的多元复合声对慢性主观性耳鸣的治疗效果，以及耳鸣频率、听力损伤"切迹"与治疗效果的关系。方法：研究对象为就诊于我院眩晕耳鸣门诊的慢性主观性耳鸣患者78例，其纯音测听阈值正常，均接受了3个月的个性化定制复合声治疗。治疗前对其进行精细化听力学检测（包括精细化纯音测听、耳鸣匹配、残余抑制），并于治疗前、治疗第30天和第90天进行耳鸣残疾量表评估（THI）。结果：①78例患者，治疗前THI评分为24.62±15.65，治疗第30天为15.82±13.02，第90天为13.62±10.98，治疗第30天、第90天的THI评分较治疗前均显著性下降（P<0.01），但第30天和第90天的THI评分差异无统计学意义（P>0.05）。②耳鸣患者的性别、年龄及耳鸣侧别对耳鸣的个性化复合声治疗的疗效无影响（P>0.05）。③78例患者的精细化纯音听阈测试，有损伤"切迹"的31例，无"切迹"的47例，2组之间的THI评分在治疗第30天和第90天差异均无统计学意义（P>0.05），提示纯音测听损伤"切迹"对耳鸣的个性化复合声治疗的疗效无影响。④31例有切迹的患者，22例耳鸣频率位于"切迹"频率范围内，9例位于"切迹"频率范围之外，治疗第30天2组之间的疗效差异有统计学意义（P<0.05）。治疗第30天，有4例"切迹"在耳鸣频率之外的患者耳鸣频率发生改变，漂移至切迹频率范围之内，其频率漂移在治疗第90天有显著性差异（P<0.05）。结论：个性化定制的复合声治疗能够降低慢性主观性耳鸣患者的THI评分，改善由于耳鸣症状产生的影响和困扰，且耳鸣频率分布在听力损伤频率范围的患者声治疗效果较好。
- 耳鸣 /
- 声治疗 /
- 个性化 /
- 治疗效果
Abstract: Objective: To explore the effect of individualized multi-compound sound therapy on chronic subjective tinnitus and the relationship between tinnitus frequency, "notch" hearing loss and the treatment effect of sound therapy. Method: Seventy-eight cases of chronic subjective tinnitus with the pure tone test threshold (PTA)in normal range (≤ 25 dB HL)were enrolled in this study. Their hearing threshold were re-evaluated using the precise pure-tone audiogram (P-PTA). Tinnitus was evaluated on pitch and loudness matching, and the effectiveness of tinnitus was measured using Tinnitus Handicap Inventory (THI) before they received the individualized customized multi-compound sound therapy for 3 months. THI were re-evaluated on the 30th day and 90th day after treatment. Result: ①The averaged THI score of these patients before the sound treatment was 24.62±15.65 (n=78). The score dropped significantly to 15.82±13.02 and 13.62 ±10.98 on the 30th day and 90th day after treatment, respectively (P<0.01). ②Patient's gender, age, and the side of tinnitus has no effect on the sound treatment of tinnitus. ③Of these 78 tinnitus patients, 31 patients who showed "notch" hearing loss and 47 patients without "notch" hearing loss in the P-PTA. The averaged THI score between the patients with and without "notch" showed no statistical difference after the treatment (P>0.05). These data suggested that "notch" hearing loss in P-PTA has no effect on the sound therapy.④Of 31 tinnitus patients with "notch" hearing loss, the tinnitus frequency of 22 cases was at the "notch" hearing loss and that of 9 cases was not at the "notch" hearing loss. Sound treatment showed significant between the former and the latter(P<0.05). After 30 days of treatment, tinnitus frequency of four patients whose tinnitus was not at the notch hearing loss drifted to the "notch" hearing loss frequency.Conclusion: Customized multi-compound sound therapy can reduce the THI score of chronic subjective tinnitus patients. The treatment reduced patient's anxiety and improved their quality of life. Sound treatment showed a better improvement in the patients whose tinnitus frequency was located at their notch hearing loss.
- tinnitus /
- sound therapy /
- individuation /
- treatment effectiveness

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