面部原发基底细胞癌的临床特征及手术治疗

韦明壮, 罗绮宁, 黄嘉韵, 等. 面部原发基底细胞癌的临床特征及手术治疗[J]. 临床耳鼻咽喉头颈外科杂志, 2018, 32(4): 279-281. doi: 10.13201/j.issn.1001-1781.2018.04.008
引用本文: 韦明壮, 罗绮宁, 黄嘉韵, 等. 面部原发基底细胞癌的临床特征及手术治疗[J]. 临床耳鼻咽喉头颈外科杂志, 2018, 32(4): 279-281. doi: 10.13201/j.issn.1001-1781.2018.04.008
WEI Mingzhuang, LUO Qining, HUANG Jiayun, et al. The clinical features and surgical treatment of facial basal cell carcinoma[J]. J Clin Otorhinolaryngol Head Neck Surg, 2018, 32(4): 279-281. doi: 10.13201/j.issn.1001-1781.2018.04.008
Citation: WEI Mingzhuang, LUO Qining, HUANG Jiayun, et al. The clinical features and surgical treatment of facial basal cell carcinoma[J]. J Clin Otorhinolaryngol Head Neck Surg, 2018, 32(4): 279-281. doi: 10.13201/j.issn.1001-1781.2018.04.008

面部原发基底细胞癌的临床特征及手术治疗

详细信息
    通讯作者: 韦明壮,E-mail:fsweimz@163.com
  • 中图分类号: R739.81

The clinical features and surgical treatment of facial basal cell carcinoma

More Information
  • 目的:探讨面部五官原发基底细胞癌(BCC)的临床特征及合理的手术治疗方案。方法:总结分析37例面部五官部位原发BCC的临床特征。手术切除原发病灶,术中冷冻病检,保证切缘干净;选择适合的皮瓣修复缺损。结果:术后随访12~36个月。37例中2例侧切缘见癌细胞残留,于术后4~6个月局部复发,局部复发率5.41%(2/37),治愈率94.59%(35/37)。切除后缺损区选用合适皮瓣修复,4例出现边缘部分坏死,经换药处理后愈合;其余全部皮瓣成活,外观效果满意。结论:面部五官原发BCC临床特征多种多样。首次彻底切除原发灶、保证切缘干净是治疗成功的关键;选择适合的方法修复缺损,可取得满意疗效。
  • 加载中
  • [1]

    彭玉成, 岳波, 范静平, 面颈部基底细胞癌48例临床分析[J].临床耳鼻咽喉科杂志, 2008, 22(12):567-568.

    [2]

    LANOUE J, GOLDENBERG G.Basal Cell Carcinoma:A Comprehensive Review of Existing and Emerging Nonsurgical Therapies[J].J Clin Aesthet Dermatol, 2016, 9:26-36.

    [3]

    SINGAL A, DAULATABAD D, PANDHI D, et al.Facial Basal Cell Carcinoma Treated with Topical 5%Imiquimod Cream with DermoscopicEvaluation[J].J Cutan Aesthet Surg, 2016, 9:122-125.

    [4]

    CHRISTENSON L J, BORROWMAN T A, VACHON C M, et al.Incidence of basal cell and squamous cell carcinomas in a population younger than 40years[J].JAMA, 2005, 294:681-690.

    [5]

    WU T P, STEIN J A.Nonmelanoma skin cancer in young women[J].J Drugs Dermatol, 2013, 12:568-572.

    [6]

    SCRIVENER Y, GROSSHANS E, CRIBIER B.Variations of basal cell carcinomas according to gender, age, location and histopathological subtype[J].Br J Dermatol, 2002, 147:41-47.

    [7]

    MARZUKA A G, BOOK S E.Basal cell carcinoma:pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management[J].Yale J Biol Med, 2015, 88:167-179.

    [8]

    RUBIN A I, CHEN E H, RATNER D.Basal-cell carcinoma[J].N Engl J Med, 2005, 353:2262-2269.

    [9]

    NEWLANDS C, CURRIE R, MEMON A, et al.Non-melanoma skin cancer:United Kingdom National Multidisciplinary Guidelines[J].J Laryngol Otol, 2016, 130:S125-S132.

    [10]

    TELFER N R, COLVER G B, MORTON C A, et al.Guidelines for the management of basal cell carcinoma[J].Br J Dermatol, 2008, 159:35-48.

    [11]

    CHUNG S.Basal cell carcinoma[J].Arch Plast Surg, 2012, 39:166-170.

    [12]

    VOICU C, MIHAI M, LUPU M, et al.Pigmented Paraaxillary Located "Complex" Basal Cell Carcinoma Imitating clinically irritatedMelanocytic Lesion-Succesfull Surgical Approach in Bulgarian Patient[J].Open Access Maced J Med Sci, 2017, 5:497-500.

    [13]

    DOURMISHEV L A, RUSINOVA D, BOTEV I.Clinical variants, stages, and management of basal cell carcinoma[J].Indian Dermatol Online J, 2013, 4:12-17.

    [14]

    CHREN M M, LINOS E, TORRES J S, et al.Tumor recurrence 5years after treatment of cutaneous basal cell carcinoma and squamous cell carcinoma[J].J Invest Dermatol, 2013, 133:1188-1196.

    [15]

    SILVERMAN M K, KOPF A W, BART R S, et al.Recurrence rates of treated basal cell carcinomas.Part3:Surgical excision[J].J Dermatol Surg Oncol, 1992, 18:471-476.

    [16]

    BENATAR M, DUMAS P, CARDIO-LECCIA N, et al.Interest and reliability of frozen section biopsy in the treatment of skin tumors[J].Ann Chir Plast Esthet, 2012, 57:125-131.

    [17]

    FLAVIO B L, CAMILA F, GILBERTO P C.Surgical treatment of basal cell carcinoma:an algorithm based on the literature[J].An Bras Dermatol, 2015, 90:377-383.

    [18]

    VENTURINI M, GUALDI G, ZANCA A, et al.A new approach for presurgical margin assessment by reflectance confocal microscopy of basal cell carcinoma[J].Br J Dermatol, 2016, 174:380-385.

    [19]

    ITO T, INATOMI Y, NAGAE K, et al.Narrowmargin excision is a safe, reliable treatment for welldefined, primary pigmented basal cell carcinoma:an analysis of 288lesions in Japan[J].J Eur Acad Dermatol Venereol, 2015, 29:1828-1831.

    [20]

    FLAVIO B L, CAMILA F, GILBERTO P C.Analysis of effectiveness of a surgical treatment algorithm for basal cell carcinoma[J].An Bras Dermatol, 2016, 91:726-731.

    [21]

    LUZ F B, FERRON C, CARDOSO G P.Surgical treatment of basal cell carcinoma:an algorithm based on literature[J].An Bras Dermatol, 2015, 90:377-383.

    [22]

    GULLETH Y, GOLDBERG N, SILVERMAN R P, et al.What is the best surgical margin for a Basal cell carcinoma:a meta-analysis of the literature[J].Plast Reconstr Surg, 2010, 126:1222-1231.

  • 加载中
计量
  • 文章访问数:  155
  • PDF下载数:  36
  • 施引文献:  0
出版历程
收稿日期:  2017-09-18

目录