交通相关空气污染与变应性鼻炎

刘果; 刘世喜

doi:10.13201/j.issn.1001-1781.2018.02.018

交通相关空气污染与变应性鼻炎

刘果,
刘世喜^,

- 四川大学华西医院耳鼻咽喉头颈外科(成都, 610041)
基金项目:
四川省卫生和计划生育委员会科研课题（No：17PJ530）

详细信息

通讯作者: 刘世喜,E-mail:liushixi1312@163.com

中图分类号: R765.21

收稿日期: 2017-09-12

Traffic-related air pollution and allergic rhinitis

LIU Guo,
LIU Shixi^,

More Information

Corresponding author: LIU Shixi, E-mail: liushixi1312@163.com

Received Date: 12 September 2017

摘要

- 鼻炎,变应性 /
- 交通相关空气污染 /
- 上皮细胞 /
- 树突细胞 /
- 可吸入性颗粒
Abstract: Exposure to traffic-related air pollutants (TRAP) has been implicated in airway allergic diseases. Recent findings include epidemiologic and mechanistic studies that shed new light on the impact of TRAP on allergic rhinitis (AR) and the biology underlying this impact. These studies have found that oxidative stress induced by TRAP could affect the axis of epithelial cell-dendritic cell-T cell towards a T-helper 2 immune response, which is the major mechanism between TRAP and AR. Further, epigenetics and microRNA might be involved in this process. Our review will summarize the most recent findings in each of these areas.
- rhinitis, allergic /
- traffic-related air pollutants /
- epithelial cells /
- dendritic cells /
- particulate matter

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参考文献(40)

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