Recent advances in early diagnosis of head and neck cancer in precision medicine era
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Abstract: Head and neck squamous cell carcinoma, HNSCC, has high morbidity and mortality.Even in America, more than 1/2 to 2/3 patients have been diagnosed at advanced stage.So, it's urgent to find ways to diagnose HNSCC earlier and foresee the curative effect.With the achievement of Next-Generation Sequencing, researchers are trying to develop early diagnostic technology from a new perspective, such as personal genomics, proteomics, metabolomics and other related personal information.Here we reviewed the recent research in early diagnosis of HNSCC.
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[1] MYDLARZ W K, HENNESSEY P T, CALIFANOJ A.Advances andperspectives in the molecular diagnosis of head and neck cancer[J].Expert Opin Med Diag, 2010, 4:53-65.
[2] CLEVERS H, NUSSE R.Wnt/β-Catenin signaling and disease[J].Cell, 2012, 149:1192-1205.
[3] CONLEY B A, DOROSHOW J H.Molecular analysis for therapy choice:NCI MATCH[J].Semin Oncol, 2014, 41:297-299.
[4] CONTICELLO S G.The AID/APOBEC family of nucleic acid mutators[J].Genome Biol, 2008, 9 (6):229.
[5] DEMEHRI S, TURKOZ A, MANIVASAGAM S, et al.Elevated epidermal thymic stromal lymphopoietin level establish an antitumor environment in the skin[J].Cancer Cell, 2012;22:494-505.
[6] GAO J, ASKOY B A, DOGRUSOZ U, et al.Integrative analysis of complex cancer genomics and clinical profiles using the cBioportal[J].Sci Signal, 2013, 6:pl1.
[7] FANJUL-FERNANDEZ M, QUESADA V, CABA-NILLAS R, et al.Cell-cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas[J].Nat Commun, 2013, 4:2531.
[8] IZUMCHENKO E, SUN K, JONES S, et al.Notch1 mutations are drivers of oral tumorigenesis[J].Cancer Prev Res (Phila), 2015, 8:277-286.
[9] KALLIONIEMI O P, KALLIONIEMI A, SUDARD, et al.Comparative genomic hybridization:A rapid new method for detecting and mapping DNA amplification in tumors[J].Semin Cancer Biol, 1993, 4:41-46.
[10] LI Z, XIAO J, HU K, et al.FBXW7 acts as an independent prognostic marker and inhibits tumor growth in human osteosarcoma[J].Int J Mol Sci, 2015, 16:2294-2306.
[11] XU Y, YU J, LIU T, et al.Loss of FBXW7 is related to the susceptibility and poor prognosis of cervical squamous carcinoma[J].Biomarkers, 2016, 21:379-385.
[12] KANEDA Y, SHIMAMOTO H, MATSUMURA K, et al.Role of caspase 8as a determinant in chemosensitivity of p53-mutated head and neck squamous cell carcinoma cell lines[J].J Med Dent Sci, 2006, 53:57-66.
[13] WORSHAM M J, STEPHEN J K, CHEN K M, et al.Delineating an epigenetic continuum in head and neck cancer[J].Cancer Lett, 2014, 342:178-184.
[14] GAYKALOVA D A, VATAPALLI R, WEI Y, et al.Outlier analysis defines zinc finger gene family dna methylation in tumors and saliva of head and neck cancer patients[J].PLoS One, 2015, 10:e0142148.
[15] UMAIR A, TARAKJI B, IBRAHIM A, et al.Quantitative study of epigenetic signature in head and neck squamous cell carcinoma[J].Turk J Med Sci, 2015, 45:372-386.
[16] PIERINI S, JORDANOV S H, MITKOVA A V, et al.Promoter hypermethylation of CDKN2A, MGMT, MLH1, and DAPK genes in laryngeal squamous cell carcinoma and their associations with clinical profiles of the patients[J].Head Neck, 2014, 36:1103-1108.
[17] STEINMANN K, SANDNER A, SCHAGDARSUREN-GIN U, et al.Frequent promoter hypermethylation of tumor-related genes in head and neck squamous cell carcinoma[J].Oncol Rep, 2009, 22:1519-1526.
[18] BRIEGER J, MANN S A, PONGSAPICH W, et al.Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells[J].Int J Mol Med, 2012, 29:505-509.
[19] SUPIC G, KOZOMARA R, JOVIC N, et al.Prognostic significance oftumor-related genes hypermethylation detected in cancer-free surgicalmargins of oral squamous cell carcinomas[J].Oral Oncol, 2011, 47:702-708.
[20] WEISS D, STOCKMANN C, SCHRODTER K, et al.Protein expression andpromoter methylation of the candidate biomarker TCF21 in head and necksquamous cell carcinoma[J].Cell Oncol (Dordr), 2013, 36:213-224.
[21] JONES W, BIANCHI K.Aerobic glycolysis:beyond proliferation[J].Front Immunol, 2015, 6:227.
[22] GOURIN C G, WATTS T L, WILLIAMS H T, et al.Identification of distant metastases with positronemission tomography-computed tomography in patients with previously untreated head and neck cancer[J].Laryngoscope, 2008, 118:671-675.
[23] BAER S, CASAUBON L, SCHWARTZ M R, et al.Glut3 expression in biopsy specimens of laryngeal carcinoma is associated with poor survival[J].Laryngoscope, 2002, 112:393-396.
[24] ESTILO C L, OC P, TALBOT S, et al.Oral tongue cancer gene expression profiling:Identification of novel potential prognosticators by oligonucleotide microarray analysis[J].BMC Cancer, 2009, 9:11.
[25] BRIZEL D M, SCHROEDER T, SCHER R L, et al.Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer[J].Int J Radiat Oncol Biol Phys, 2001, 51:349-353.
[26] QUENNET V, YAROMINA A, ZIPS D, et al.Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice[J].Radiother Oncol, 2006, 81:130-135.
[27] SCHOORS S, BRUNING U, MISSIAEN R.Fatty acid carbon is essential for dNTP synthesis in endothelial cells[J].Nature, 2015, 520:192-197.
[28] SAHEBJAMEE M, ESLAMI M, ATARBASHIMO-GHADAM F, et al.Salivary concentration of TNF-alpha, IL-1alpha, IL-6, and IL-8in oral squamous cell carcinoma[J].Med Oral Patol Oral Cir Bucal, 2008, 13:E292-295.
[29] KUROPKAT C, PLEHN S, HERZ U, et al.Tumor marker potential of serum matrix metalloproteinasesin patients with head and neck cancer[J].Anticancer Res, 2002, 22:2221-2227.
[30] LEE K D, LEE H S, JEON C H.Body Fluid Biomarkers for Early detectionof head and neck squamous cell carcinomas[J].Anticancer Res, 2011, 31:1161-1168.
[31] PARK N J, ZHOU H, ELASHOFF D, et al.Salivary microRNA:Discovery, characterization, and clinical utility for oral cancer detection[J].Clin Cancer Res, 2009, 15:5473-5477.
[32] YUASA Y, NAGASAKI, AKIYAMA Y, et al.DNA, methylation sataus is inversely correlated with green tea intake and physical activity in gastric cancer patients[J].Int J Cancer, 2009, 124:2677-2682.
[33] ZENG H, IRWIN M L, LU L, et al.Physical activity and breast cancer survival:an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1[J].Breast Cancer Res Treat, 2012, 133:127-135.
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