Endoscopic transoral resection the tumors of the higher position in parapharyngeal space: a retrospective case-control study
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摘要: 目的:探讨经口翼突进路内镜下切除颈鞘内侧高位咽旁间隙肿瘤的安全性和指征。方法:收集11例行经口翼突进路全程内镜下高位咽旁间隙肿瘤切除的患者作为研究组。选取同期同样大小和位置的咽旁间隙肿瘤传统径路切除患者以1:1配对作为回顾性对照研究。比较2组的整块切除率、手术时间、术中出血量、术后住院时间、并发症等情况,并进行统计学分析。结果:研究组手术时间为(122.45±22.2)min,术中出血量为(97.26±13.75)ml,术后住院时间(4.09±1.22)d;对照组手术时间为(134.36±20.38)min,术中出血量为(213.64±63.99)ml,术后住院时间(5.10±0.99)d。2组均有分块切除患者。研究组有1例血管纤维瘤患者术后半年复发。研究组术中出血量要少于对照组。2组患者平均手术时间、整块切除率及术后住院时间没有明显差别。结论:经口翼突径路内镜下切除颈鞘内侧的高位咽旁间隙良性肿瘤是可行的,具有视野清楚、损伤小、安全性高及不留外部瘢痕等优点。Abstract: Objective: To analysis the indication and security of the endoscopic resection of transoarl and pterygoid process approach of neoplasms in elevatus parapharyngeal space.Method: A retrospective case-control study were carried out in 22 patients with parapharyngeal space tumors.In the observation group(11 patients),tumors were endoscopic resected by transoral and pterygoid process approach. Paired with 11 patients(control group) who underwent surgry by traditional approach. We compared the en bloc resection rate, the operation time, blood loss, postoperative hospital stay, complication rate between the two groups.Result: In the observation group,the operation time, the blood loss and the postoperative hospital stay was(122.45±22.2)min,(97.26±13.75)ml, (4.09±1.22)d respectively. While in the control group, the operation time, the blood loss and the hospitalized days was(134.36±20.38)min,(213.64±63.99)ml,(5.10±0.99)d respectively. There were tumors that were block resection in both groups. In the observation group, there were a recurrence. Comparing the operation time, en bloc resection rate and postoperative hospital stay,there were no significant differences. There were differences in bloods loss between the two groups.Conclusion: The endoscopic transoral resection the tumors of the higher position in parapharyngeal space is safe,minimally invasive and feasible in selected cases,with a high local control rate and a low surgical complication rate.
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