141例病毒感染性嗅觉障碍患者的临床特征分析

田俊; 魏永祥; 李丽; 孙智甫; 王斌全

doi:10.13201/j.issn.1001-1781.2017.10.003

141例病毒感染性嗅觉障碍患者的临床特征分析

- 1 山西医科大学(太原, 030001);
- 2 首都医科大学附属北京安贞医院耳鼻咽喉头颈外科;
- 3 首都医科大学附属北京朝阳医院耳鼻咽喉头颈外科
基金项目:
国家自然科学基金(No:81271062)

详细信息

通讯作者: 田俊,E-mail:zguotian@126.com

中图分类号: R765.6

收稿日期: 2016-12-28

Analysis of clinical characteristics of 141 patients with postviral olfactory dysfunction

- 1 Shanxi Medical University, Taiyuan, 030001, China;
- 2 Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University;
- 3 Department of Otolaryngology Head and Neck Surgery, Beijing Chaoyang Hospital, Capital Medical University

More Information

Corresponding author: TIAN Jun, E-mail: zguotian@126.com

Received Date: 28 December 2016

摘要

摘要: 目的: 探讨病毒感染后嗅觉障碍(PVOD)患者的临床特征。方法: 收集并分析2009-07-2015-01期间就诊的连续141例PVOD患者的病例信息,包括调查问卷获取一般信息及发病症状,主观嗅觉心理测试采用Sniffin'Sticks Test。结果: 回顾性分析连续就诊的141例PVOD患者, 男女比例为1.0:2.3,嗅觉障碍严重程度在男女间无差别(χ²=0.05,P>0.05)。患者年龄在30~40岁、50~60岁有集中的趋势。鼻塞、鼻涕、喷嚏是PVOD最常见的鼻部症状,咽痛、咳痰、咳嗽是最常见的其他症状。结论: 大样本PVOD患者的临床特点分析进一步提示PVOD的发生可能和性别、年龄等因素有关,但目前我们对这种复杂疾病的认识十分有限,需要进一步的研究。
- 嗅觉障碍 /
- 病毒 /
- 上呼吸道感染 /
- 症状
Abstract: Objective: The aim of this study is to investigate the clinical features of the patients with postviral olfactory dysfunction(PVOD).Method: Clinical information of 141 consecutive outpatients with PVOD were collected and analyzed based on a questionnaire, including age, gender, months of onset, and symptoms. Sniffin'Sticks Test was used as a psychophysical olfactory test to evaluate olfactory function.Result: Retrospective analysis of 141 patients with PVOD, the male to female ratio of patients was 1.0:2.3. The severity of olfactory dysfunction was found no significant difference between the man and the women(χ²=0.05,P>0.05). Patients aged from 30 to 40 years old and 50 to 60 years of age were vulnerable to PVOD. The most common nasal symptoms at the times of upper respiratory infection(URI) were nasal obstruction, rhinorrhea and sneezing, together with other symptoms, such as sore throat, sputum and cough.Conclusion: Analysis of clinical characteristics in a large sample shows that gender, age may be related to PVOD. However, our understanding of this complex disease is still limited and much more studies are necessary.
- olfactory dysfunction /
- virus /
- upper respiratory infection /
- symptoms

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