累及鼻中隔的Rosai-Dorfman病2例

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收稿日期: 2016-11-17

Rosai-Dorfman disease with nasal septum involvement:two cases report

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Received Date: 17 November 2016

- 鼻中隔 /
- Rosai-Dorfman病
Abstract: Clinical data of 2 cases with Rosai-Dorfman disease(RDD)originating from nasal septal mucosa were reported retrospectively,and the pertinent literature was reviewed.Without specific clinical features,RDD in nasal cavity could be misdiagnosed easily.Pathology revealed different morphologies of cell proliferation with engulfed lymphocytes,plasma cells and neutrophils.Immunohistochemical staining showed S-100(+),CD68(+),CD1(-).RDD disease generally has a benign course and is self-limited.Its diagnosis depends mainly on biopsy.As for the treatment of this disease,the strategies are not systemic and standard.Surgical treatment is used to excise the mass in nasal cavity,glucocorticoids treatment after surgery is inconclusive.The long-term effect need to be further observed.
- nasal septal /
- Rosai-Dorfman disease

[1]	建渤, 刘卫平, 左卓. Rosai-Doffman病的临床病理、免疫表型和病原学观察[J].中华病理学杂志,2007,36(1):33-38.
[2]	AKYIGIT A, AKYOL H, SAKALLIOGLU O,et al. Rosai-Dorfman disease originating from nasal septal mucosa[J]. Case Rep Otolaryngol,2015,2015:232-289.
[3]	GAITONDE S. Multifocal, extranodal sinus histiocytosis with massive lymphadenopathy:an overview[J].Arch Pathol Lab Med, 2007,131:1117-1121.
[4]	陈琼荣, 杨菲, 王明伟, 等.Rosai-Dorfman病误诊为鼻硬结症一例[J].中华耳鼻咽喉头颈外科杂志,2010,45(5):338-339.
[5]	明伟, 袁虎, 王洪田, 等.鼻腔鼻窦结外Rosai-Doffman病一例[J].中华耳喉头颈外科杂志,2010,45(1):73-74.
[6]	许振跃,洪斌,林金成.以鼻出血为主要症状的鼻腔Rosai.Dorfman病一例[J]. 中华耳鼻咽喉头颈外科杂志, 2012,47(11):955-956.
[7]	PULSONI A,ANGHE L G, FALCUCCI P, et al. Treatment of sinus histiocytosis with massive lymphadenopathy(rosai-dorfman disease):report of a case and literature review[J]. Am J Hematol, 2002, 69:67-71.
[8]	DUVAL M, NGUYEN V H, DANIEL S J. Rosai-dorfman disease:an uncommon cause of massive cervical adenopathy in a two-yearold female[J]. Otolaryngol Head Neck Surg, 2009, 140:274-275.