鼻咽癌残留的保守治疗与鼻内镜下手术治疗的效果与安全性分析

李丹

doi:10.13201/j.issn.1001-1781.2016.24.012

鼻咽癌残留的保守治疗与鼻内镜下手术治疗的效果与安全性分析

李丹^,

- 湖北医药学院附属东风医院耳鼻咽喉科(湖北十堰, 442008)

详细信息

通讯作者: 李丹,E-mail:lidan615@yeah.net

中图分类号: R739.63

收稿日期: 2016-08-24

Efficacy and safety of conservative and nasal endoscopic therapy for residual nasopharyngeal carcinoma

LI Dan^,

- Department of Otolaryngology, Dongfeng Hospital, Hubei University of Medicine, Shiyan, 442008, China

More Information

Corresponding author: LI Dan, E-mail: lidan615@yeah.net

Received Date: 24 August 2016

摘要

摘要: 目的:对比鼻咽癌残留的保守治疗与鼻内镜下手术治疗的效果与安全性。方法:鼻咽癌残留患者82例,根据入院顺序分为鼻内镜组与挽救性放疗组各41例。挽救性放疗组给予放疗保守治疗,鼻内镜组给予鼻内镜下手术治疗,观察两组的预后疗效与并发症发生情况。结果:治疗6个月后鼻内镜组与挽救性放疗组的有效率分别为92.7%和75.6%,鼻内镜组的有效率高于挽救性放疗组(P<0.05)。两组均未出现鼻咽部大出血及邻近重要器官损伤等严重并发症,其他并发症经对症处理后好转。鼻内镜组的总生存时间、局部无复发生存时间及远处无转移生存时间分别为(34.24±2.19)个月、(28.45±1.98)个月和(26.33±2.88)个月,均明显高于挽救性放疗组的(26.46±1.98)个月、(21.87±2.09)个月和(20.44±3.19)个月(P<0.05)。结论:相对于保守放疗,鼻内镜下手术治疗鼻咽癌残留能提高疗效,安全性良好,延长了患者的生存时间,有很好的应用价值。
- 鼻咽肿瘤 /
- 放射治疗 /
- 内镜外科手术 /
- 并发症
Abstract: Objective: To compare the efficacy and safety of conservative and nasal endoscopic therapy for residual nasopharyngeal carcinoma.Method: Eighty-two cases of residual nasopharyngeal carcinoma patients in our hospital were selected and according to the order of admission were equally divided into the nasal endoscopy group and the conservative group with 41 cases in each, the conservative group were given conservative treatment of radiotherapy and the nasal endoscopy group were given nasal endoscopic surgery, the effects, prognosis and complications were observed in the two groups.Result: The effective rates of nasal endoscopic group and conservative group were 92.7% and 75.6% after treatment for 6 moths, and the effective rate of nasal endoscopic group was significantly higher than that in conservative group (P<0.05). There were no serious complications such as massive hemorrhage of nose and throat and major organ damage in the two groups, and other complications were improved after symptomatic treatment. The overall survival, local recurrence free survival time and distant metastasis free survival time in the nasal endoscopic group were (34.24±2.19) months, (28.45±1.98) months and (26.33±2.88) months, were significantly higher than those of the conservative group (26.46±1.98) months, (21.87±2.09) months and (20.44±3.19) months(P<0.05).Conclusion: Compares with conservative radiotherapy, nasal endoscopic surgery in the treatment of residual nasopharyngeal carcinoma can improve the efficacy and safety, so as to prolong the survival time of patients that has good application values.
- nasopharyngeal neoplasms /
- radiotherapy /
- endoscopic surgical procedures /
- complications

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