变应性鼻炎动物模型的研究进展

栾兆磊; 王雨农; 王洪田

doi:10.13201/j.issn.1001-1781.2016.13.022

变应性鼻炎动物模型的研究进展

- 解放军总医院耳鼻咽喉头颈外科(北京, 100853)
基金项目:
国家自然科学基金项目(No:81371074)

详细信息

通讯作者: 王洪田,E-mail:wht301@263.net

中图分类号: R765.21

收稿日期: 2016-04-22

Research progress of animal model of allergic rhinitis

More Information

Corresponding author: WANG Hongtian, E-mail: wht301@263.net

Received Date: 22 April 2016

摘要

- 鼻炎 /
- 变应性 /
- 动物模型 /
- 综述 /
- 研究进展
Abstract: The animal model of allergic rhinitis is ciritical for the study of this disease.Guinea pig,mouse,rat,rabbit and other animals can be selected.Allergen includes ovalbumin,pollen,dust mites,available fungi,roundworm and schistosome antigen.Aluminum hydroxide adjuvant is most commonly used.To enhance the sensitivity,nasal drops can be selected,inhalation and multi-point subcutaneous injection is optional.Nasal itching,sneezing,clear nasal discharge,or specific histopathological and immunological results can indicate the success of modeling.Immunological test is the most important standard to determine whether the model is successful or not.This review summarizes the recent advances in the study of animal models of allergic rhinitis.
- rhinitis /
- allergic /
- animal model /
- review /
- research progress

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