-
摘要: 目的: 探讨冷冻治疗鼻腔粘连的临床效果。方法: 随机选取68侧鼻腔粘连患者,分为实验组和对照组。实验组采用接触冷冻治疗鼻腔粘连,对照组采用常规鼻腔粘连分解术,分别在术前、术后行鼻阻塞症状评估(NOSE量表)和治疗期间整体不适感视觉模拟量表(VAS)评分;术后1、3、8周分别行鼻内镜检查观察鼻腔粘连处黏膜愈合情况并打分。结果: ①2组间NOSE量表评分术前差异无统计学意义(P>0.05),术后差异有统计学意义(P<0.05),实验组优于对照组;②治疗过程中整体不适感实验组优于对照组,VAS评分比较差异有统计学意义(P<0.05);③术后1、3、8周鼻内镜检查评分2组间均差异有统计学意义(P<0.05),各时间点实验组优于对照组;④实验组首次治愈率为97.1%,对照组首次治愈率为76.5%,2组比较差异有统计学意义(P<0.05)。结论: 冷冻治疗鼻腔粘连安全有效、简便易操作,术后黏膜转归良好,能提高手术治愈率,减轻患者痛苦,更易为患者所接受。Abstract: Objective: To investigate the effect of cryotherapy in the treatment of nasal cavity adhesion.Method: Patients with nasal cavity adhesion(68 sides in total)were randomly devided into the experimental group(34 sides) and the control group(34 sides). The experimental group were treated with cryotherapy and the control group with traditional separation surgery. The subjective symptoms and recovery of nasal mucosa were observed at 1, 3 and 8 weeks after treatment.Result: ①The postoperative nasal obstruction symptom evaluation score in the experiment group were significantly better than in the control group(P<0.05). ②The VAS score of discomfort during therapeutic process in the experiment group were significantly better than in the control group(P<0.05). ③The endoscopic mucosa morphology score at 1,3 and 8 weeks postoperatively in the experiment group was significantly better than that in the control group(P<0.05).④The cure rate of experiment group was 97.1% and 76.5% of control group.The cure rate of experiment group was significantly higher than that of the control group(P<0.05).Conclusion: Cryotherapy is a simple and safe therapeutic method in the treatment of nasal cavity adhesion with less discomfort, higher therapeutic effect and better mucosa recovery. Cryotherapy is more likely to be accepted by patients.
-
Key words:
- nasal cavity adhesion /
- cryotherapy /
- nasal mucosa
-
-
[1] 韩德明,周兵.鼻内镜外科学[M].北京:人民卫生出版社,2001:206-216.
[2] 孙军达,方军.鼻内窥镜术后鼻腔粘连对疗效的影响及粘连的相关因素分析[J].中国医师杂志,2013,15(3):411-413.
[3] 冯善顶,刘秋润.鼻腔粘连的治疗和预防[J].临床耳鼻咽喉科杂志,2004,18(2):122-124.
[4] STEWART M G,WITSELL D L,SMITH T L,et al.Development and validation of the Nasal Obstruction Symptom Evaluation(NOSE)scale[J].Otolaryngol Head Neck Surg,2004,130:151-153.
[5] 董栋,赵玉林,MICHAE G,等.鼻阻塞症状评估(NOSE)量表中文版的研制[J].中华耳鼻咽喉头颈外科杂志,2014,49(1):20-26.
[6] WANG H,ZHANG N,TAO M,et al.Application of interventional bronchoscopic therapy in eight pediatric patiens with malignant airway tumors[J].Tumori,2012,98:581-587.
[7] 倪彩云,刘霞,马静,等.支气管镜下冷冻治疗儿童肉芽及瘢痕组织导致的下气道狭窄及阻塞22例[J].中华儿科杂志,2012,50(1):45-49.
[8] 郭玉德.实用冷冻疗法[M].2版.北京:人民卫生出版社,2006:354-357.
[9] 周阔,梁珺,崔爱华,等.支气管镜下氩气刀冷冻联合治疗儿童气管插管后严重气道狭窄一例及文献复习[J].中华儿科杂志,2013,51(10):771-774.
[10] 姜博仁,武卫东.低温冷冻刀降温方法综述及展望[J].低温与超导,2012,40(1):13-17.
-
计量
- 文章访问数: 165
- PDF下载数: 87
- 施引文献: 0
下载: