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Abstract: Clinical data of two cases of relapsing polychondritis were reported and the relative literatures were reviewed. The two patients diagnosed relapsing polychondritis after clinical and laboratory examinations.The first case was mild, no larynx and trachea involvement, and her condition improved and controlled after glucocorticoid treatment;The second case which involved larynx and trachea caused breathing difficulty. Two years later he died of lung infection and respiratory failure despite a variety of treatment methods. Relapsing polychondritis is very easily misdiagnosed, early diagnosis and treatment can slow the progression of the disease, for patients with violations of the larynx and trachea should pay close attention to disease progression, tracheotomy or place endotracheal memory alloy stent when necessary.
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Key words:
- relapsing polychondritis /
- diagnosis /
- treatment /
- corticosteroid
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[1] 李胜光,刘湘源,黄烽.复发性多软骨炎20例临床分析[J].中华风湿病学杂志,2002,6(1):37-39.
[2] 顾美珍,殷善开.复发性多软骨炎[J].罕少疾病杂志,2004,11(1):39-42.
[3] BUCKNER J H,WU J J,REIFE R A,et al.Autoreactivity against matrilin-1in a patient with relapsing polychondritis.Arthritis Rheum,2000,43:939-943.
[4] BACHOR E,BLEVINS N H,KARMODY C,et al.Otologic manifestations of relapsing polychondritis.Review of literature and report of nine cases[J].Auris Nasus Larynx,2006,33:135-141.
[5] TSUDA T,NAKAJIMA A,BABA S,et al.A case of relapsing polychondritis with bilateral sensor neural hearing loss and perforation of the nasal septum at the onset[J].Mod Rheumat ol,2007,17:148-152.
[6] LET KO E,ZAFRIAKIS P,BALT AT ZIS S,et al.Relapsing polychondritis:a clinical review[J].Sem in Arthritis Rheum,2002,3:384-395.
[7] CHANG S J,LU C C,CHUNG Y M,et al.Laryngotracheal involvement as the initial manifestation of relapsing polychondritis[J].J Chin Med Assoc,2005,68:279-282.
[8] HIRUNWIWATKUL P,TROBE J D.Optic neuropathy associated with periostitis in relapsing polychondritis[J].J Neuro-ophthalmology,2007,27:16-21.
[9] CARTER J D.Treatment of polychonfritids with a TNF antagonist[J].J Rheumatol,2005,32:1413-1413.
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