儿童变应性鼻炎伴哮喘患病率的Meta分析

魏萍; 寇巍; 姚红兵

doi:10.13201/j.issn.1001-1781.2016.09.007

儿童变应性鼻炎伴哮喘患病率的Meta分析

- 重庆医科大学附属儿童医院耳鼻咽喉头颈外科(重庆, 400014)
基金项目:
社会事业与民生保障科技创新专项（No：cstc2015shmszx120022）

详细信息

通讯作者: 姚红兵,E-mail:yaohongbing@163.net

中图分类号: R765.21

收稿日期: 2016-04-05

Meta-analysis of the morbidity of asthma in children with allergic rhinitis

- Department of Otolaryngology-Head and Neck Surgery, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China

More Information

Corresponding author: YAO Hongbing, E-mail: yaohongbing@163.net

Received Date: 05 April 2016

摘要

摘要: 目的：儿童变应性鼻炎和哮喘被认为具有相似的发病机制，但目前关于儿童变应性鼻炎伴哮喘患病率的大样本研究较少，因此该文借助循证医学的方法通过Meta分析了解儿童变应性鼻炎伴哮喘的患病率。方法：系统检索Pubmed、Science、Springer、Elsevier、Embase、BMJ Journals、万方数据库、维普数据库、中国生物医学文献数据库、中国期刊全文数据库等数据库查找关于儿童变应性鼻炎伴哮喘患病率的文献，同时追索纳入文献的参考文献。采用R3.2.3软件对各研究结果进行分析。结果：共纳入15篇Cross-sec-tional studies。Meta分析结果显示，中国变应性鼻炎患儿中伴哮喘的患病率高达35.01%（95% CI 32.32%~37.70%），国外变应性鼻炎患儿中伴哮喘的患病率达31.59%（95% CI 28.02%~35.16%）。结论：变应性鼻炎患儿伴哮喘的患病率高，中国变应性鼻炎患儿伴哮喘的患病率高于国外。
- 鼻炎,变应性 /
- 哮喘 /
- Meta分析 /
- 患病率
Abstract: Objective: Pathogenesis of allergic rhinitis(AR) is thought to be related with asthma in children. However, lager scaled reports concerned on the co-morbidity of this two diseases in children are rare. In this meta-analysis, we aim to clarify the morbidity of asthma in children with AR.Method: Pubmed, Science, Springer, Elsevier, Embase, BMJ Journals, Wanfang data, VIP, CBM and CNKI were searched for relevant studies.The prevalences of asthma in children with AR were retrieved from individual studies and the pooled estimates generated by R3.2.3.Result: Fifteen cross-sectional studies were included in the meta-analysis. The results showed that the incidences of asthma in AR children were 35.01%(95%CI 32.32%-37.70%) in China and 31.59%(95% CI 28.02%-35.16%) in foreign countries.Conclusion: Comorbidity of AR and asthma was high in children. The incidence of asthma is higher in children with AR in China than that in foreign countries.
- rhinitis, allergic /
- asthma /
- Meta-analysis /
- morbidity

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