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摘要: 目的: 探讨正常成人言语声诱发的听性脑干反应(s-ABR)各波的电生理特性,分析其与受试者噪声下言语识别能力及性别的关系。方法: 以40 ms时程的复合语音/da/为刺激声,诱发40例母语为汉语的健听成人的s-ABR,分析s-ABR各波的引出率,潜伏期、V/A斜率(V-A峰峰值与V-A波间期之比)与受试者性别的关系,以及V/A斜率与噪声下言语识别阈间的关系。结果: s-ABR引出的7个反应波形中,女性受试者的V、A、O、F波潜伏期较男性短(均P<0.05),其余各波潜伏期受性别影响小,差异无统计学意义(P>0.05);噪声下言语识别阈与V/A斜率呈负相关(r=-0.478, P<0.05),即V/A斜率越大,噪声下言语识别阈越低。结论: 言语信息中随时间快速变化的高频辅音所诱发的神经反应受性别影响明显,随时间变化较慢的低频元音部分所诱发的神经反应受性别影响小;瞬态变化信息处理能力好的受试者,其噪声下言语识别能力也越好。Abstract: Objective: To study the electrophysiological characteristics of the Auditory Brainstem Response to Speech Sounds (s-ABR) in healthy adults, and then analyze its relationship between noise speech recognition ability and sex.Method: We accessed the auditory brainstem response to a synthesized stop-consonant speech syllable/da/in 40 native-Chinese speech adults. Timing components of the response were compared between males and females to determine which aspects of the response are affected by sex. The relationship of the slope between the onset peak (V) and though (A) (V/A slope) and the noise speech recognition ability was analyzed.Result: A dissimilarity between males and females was observed in the response to the component that change rapidly over time(P<0.05).The other peaks latency except (P<0.01) was different between gender, the remaining peaks did not have statisticals differences (P>0.05). Noise speech recognition and the V/A slope was negatively correlated (r=-0.478, P<0.05), which indicated that the greater slope of V/A,the lower of the speech recognition threshold under noise.Conclusion: The verbal components change rapidly over time, and high-frequency consonants evoked neural response obviously affected by gender. In the slower changing, lower frequency information in the stimulus was minimally affected by sex.The subjects with better abilities of processing transient and rapid information can show lower noise speech recognition threshold.
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Key words:
- auditory brainstem response /
- s-ABR /
- sex difference /
- noise speech recognition
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