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摘要: 目的: 分析蝶窦囊肿患者的临床特点,使其得到早期诊断、干预和治疗,以降低误诊率。方法: 收集2000-01-2015-01期间在中南大学湘雅医院住院治疗的蝶窦囊肿患者的临床资料,并统计中国期刊全文数据库和万方数据库中有关该疾病的文献报道,进行综合分析。结果: 共收集蝶窦囊肿患者82例,伴有头痛症状52例,视力下降31例,脑神经麻痹10例,眼球突出2例,鼻部症状15例,无明显症状5例。男、女患者各症状分布差异无统计学意义(P>0.05)。45例以头痛为首发症状的患者中有18例逐渐出现了视力下降,10例伴有筛窦囊肿的患者中有8例出现了视力下降。统计文献检索到的161例及该院82例蝶窦囊肿患者,最常见的症状均为头痛,其次为视力下降。结论: 该文为目前为止我国蝶窦囊肿疾病的最大样本量研究。头痛和视力下降症状为该类疾病最常见的症状,对于出现头痛或者发现伴筛窦囊肿的蝶窦囊肿患者应注意视力改变,并建议早期手术治疗,防止视神经损伤。Abstract: Objective: Aimed to analyse the clinical features of the patients with sphenoid sinus mucocele, achieve earlier diagnosis and more timely intervention and decrease the occurrence of misdiagnoses. Method: A retrospective study was first conducted in patients with sphenoid sinus mucoele treated in Xiangya hospital from Jan 2000 to Jan 2015. Then literature reports on this disease were collected and analyzed from China National Knowledge Infrastructure (CNKI) and Wan Fang database.Result: We collected 82 patients with sphenoid sinus mucocele treated in Xiangya hospital. There were 52 patients presented with headache, 31 patients presented with visual impairment, 10 patients presented with cranial nerve palsy, 2 patients presented with exophthalmos, 15 patients presented with nasal symptoms, and 5 patients with no obvious symptoms. There was no significant difference for symptoms distribution between male and female patients (P>0.05). Among 45 patients with headache as first symptom and 10 patients with ethmoid sinus mucocele, there were 18 patients and 8 patients subsequently suffering from visual impairment, respectively. We also collected 161 patients in literature except for enrolling the 82 patients treated in Xiangya hospital, and found that headache was the most common symptom, followed by visual impairment, in the two independent cohorts. Conclusion: To the best of our knowledge, this is the study of maximum sample for sphenoid sinus mucocele in China. Headache and visual impairment are the most common symptoms for sphenoid sinus mucocele. Surgical treatment should be early performed when the desease accompanied with headache or ethmoid sinus mucocele, to avoid other complications such as visual impairment and even blindness.
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Key words:
- sphenoid sinus mucocele /
- headache /
- visual impairment
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