The roles of otolith organs in the recurrence primary benign paroxysmal positional vertigo
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摘要: 目的:通过检测前庭诱发肌源性电位(VEMPs)研究耳石器在原发性良性阵发性位置性眩晕(BPPV)发作以及复发中的作用。方法:收集2014-09-2014-11期间就诊的17例复发性原发性BPPV患者和同期就诊的42例非复发性原发性BPPV患者资料。所有患者均进行VEMP检查,包括颈肌前庭诱发肌源性电位(cVEMP)和眼肌前庭诱发肌源性电位(oVEMP)。VEMP 波形未引出或双侧不对称率>29%称为异常。结果:BPPV患者中,cVEMP与oVEMP异常率差异有统计学意义(P<0.05),oVEMP阳性率更高。复发与非复发组oVEMP异常率差异有统计学意义(P<0.01),cVEMP异常率差异无统计学意义(P>0.05)。复发与非复发组年龄及性别比较差异不存在统计学意义。结论:原发性BPPV患者耳石器尤其是椭圆囊功能受损与BPPV发生有关。椭圆囊功能异常可能与BPPV复发有关。性别及年龄段与BPPV复发不存在直接联系。
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关键词:
- 良性阵发性位置性眩晕 /
- 复发 /
- 椭圆囊 /
- 球囊 /
- 前庭诱发肌源性电位
Abstract: Objective: To explore the roles of otolith organs in the occurrence and recurrence of primary benign paroxysmal positional vertigo(BPPV)by vestibular evoked myogenic potential (VEMP) test.Method: We enrolled 17 recurrent primary BPPV patients and 42 non-recurrent primary BPPV patients between September 2014 and November 2014. All patients underwent VEMPtests, including cervicalvestibular evoked myogenic potential(cVEMP and ocular vestibular evoked myogenic potential (oVEMP) tests. The abnormal case was defined as non-elicitation or asymmetry rate between bilateral sides is larger than 29%.Result: Significant difference was found in abnormalrate between cVEMP and oVEMP(P<0.05) in BPPV patients. The abnormal rate of oVEMP was higher than that of cVEMP. Significant difference was found in abnormal rate in oVEMP test between recurrent and non-recurrent groups(P<0.01),but not in cVEMP(P>0.05).No significant difference was found in sex and age between recurrent and non-recurrent groups(P>0.05).Conclusion: The impairment of otolith organs, especially the utricle, is related to primary BPPV. Dysfunction of utricle may play a role in recurrence of BPPV. Recurrence of BPPV is not correlated with sex and age. -
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