The research on the airway hyperresponsiveness and IOS airway resistance index of industrial area resident
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摘要: 目的:针对宁波镇海工业区居民气道反应性及脉冲振荡法(IOS)测气道阻力指标情况进行调研。方法:以随访形式对镇海工业区(215例)和城区(203例)两地人群气道反应性和呼吸功能进行调研,比较分析不同区域人群的差异程度。结果:工业区215例研究对象中气道高反应性疑似者达95例,而城区203例中仅43例疑似者。工业区组95例中有47例(49.5%)为激发阳性者,而城区组43例中仅有14例(32.6%)。两区域人群在不同气道高反应性类型中的比例均差异有统计学意义(P<0.01)。城区人群在气道阻力各指标上亦均小于工业区,且均差异有统计学意义(P<0.05)。结论:工业区居民在气道高反应性患病率及IOS气道阻力方面均高于城区居民,监测和评价该地区居民上气道疾病,炎症病变程度和呼吸功能对于了解局部中重度污染区域均有一定意义。Abstract: Objective: To study airway reactivity and impulse oscillation (IOS)-measured airway resistance indicators of residents of Zhenhai industrial area in Ningbo city.Method: In the form of follow-up, both airway reactivity and respiratory functions of populations in Zhenhai industrial zone (n=215) and urban (n=203) were measured, comparing difference degree between different regions.Result: Ninty-five of 215 cases in industrial area were identified as suspected airway hyperresponsiveness, but only 43 of 203 cases were in urban areas. Forty-seven of 95 cases (49.5%) in industrial zone were positive, while only 14 cases (32.6%) in urban. The proportions of people in the two regions on different types of airway hyperresponsiveness were significantly different (P<0.01). All airway resistance indexes of urban populations were significantly lower than that of industrial zone (P<0.05).Conclusion: The prevalence of airway hyperresponsiveness and IOS airway resistance aspects of industrial area residents was higher than that of urban residents. Monitoring and evaluating the airway diseases, inflammatory lesions and respiratory function in the region were good for understanding the severe pollution in the local area in certain significance.
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Key words:
- industrial areas /
- airway hyperresponsiveness /
- airway resistance /
- histamine
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