T<sub>3</sub>、T<sub>4</sub>期声门型喉癌患者出现颈部淋巴结转移的相关因素分析

李翔宇; 王吉选; 孙海燕; 胡艳红; 王东海; 赵国锋

doi:10.13201/j.issn.1001-1781.2015.17.006

T₃、T₄期声门型喉癌患者出现颈部淋巴结转移的相关因素分析

- 1 唐山市协和医院耳鼻咽喉头颈外科(河北唐山, 063000);
- 2 华北理工大学附属医院骨科;
- 3 唐山职业技术学院耳鼻咽喉科

详细信息

通讯作者: 胡艳红,E-mail:lyb135246@126.com

中图分类号: R739.6

收稿日期: 2015-06-18

Analysis of correlated factors of cervical lymphatic metastasis of T₃ and T₄ glottic carcinoma

- 1 Department of Otolaryngology-Head and Neck Surgery, Tangshan Xiehe Hospital, Tangshan, 063000, China;
- 2 Department of Orthopedics, North China University of Sceience and Technology Affiliated Hospital;
- 3 Department of Otolaryngology, Tangshan Vocational Technical College

More Information

Corresponding author: HU Yanhong, E-mail: lyb135246@126.com

Received Date: 18 June 2015

摘要

摘要: 目的:分析T₃ 、T₄期声门型喉癌患者颈部淋巴结转移的相关因素。 方法:回顾分析91例声门型喉癌(均为鳞状细胞癌)患者的临床资料,观察患者T分期、病理分化程度及肿瘤部位对颈部淋巴结转移的影响。结果:①91例T₃ 、T₄期声门型喉癌患者颈部淋巴结总转移率为21.98%;②T₃、 T₄期患者的颈部淋巴结转移率分别为18.06%、36.84%(P>0.05);按病理分化程度分类,高、中、低分化者的颈部淋巴结转移率分别为13.89%、26.00%、40.00%(P>0.05);③肿瘤侵及声带组无转移,侵及声门及声门上组的转移率为16.22%,侵及声门及声门下组的转移率为15.38%,同时侵及声门、声门上及声门下组的转移率为46.15%(P<0.01)。结论:T₃、T₄期声门型喉癌患者颈淋巴结转移情况不完全受T分级及病理分化程度影响,当肿瘤侵及声门上区及声门下区后,颈淋巴结转移率明显增高,因此肿瘤的侵及范围是淋巴结转移的重要因素。
- 喉肿瘤 /
- 颈淋巴结 /
- 相关因素
Abstract: Objective: To analyze the correlated factors of cervical lymphatic metastasis of T₃ and T₄ glottic carcinoma.Method: We did a retrospective analysis of 91 glottic carcinoma patients' clinical data to analyze cervical lymph node metastasis on different T stage, pathologic degree and the tumor sites. Result: The cervical lymph node metastasis rate of 91 cases of T₃ and T₄ glottic carcinoma was 21.98%. T₃ group's metastasis rate was 18.06%(13/72), T₄ group's metastasis rate was 36.84%(7/19),P>0.05.Grouped according to the degree of pathological differentiation, well-differentiated squamous cell carcinoma metastasis rate is 13.89%(5/36), middle-differentiated squamous cell carcinoma metastasis rate is 26.00%(13/50), and poorly-differentiated squamous cell carcinoma metastasis rate is 40.00%(2/5),P>0.05.Cervical lymph node metastasis rate was 16.22%,when the tumor invading supraglottic region. Cervical lymph node metastasis rate was 15.38%,when the tumor invading subraglottic region. Cervical lymph node metastasis rate was 46.15%,when the tumor invading supraglottic and subraglottic region(P<0.01).Conclusion: Cervical lymph node metastasis in cN0 patient with supraglottic carcinoma is effected by T classification, cervical lymphatic metastasis of T₃ and T₄ glottic carcinoma is not entirely effected by T stage and pathologic degree.When the tumor invades supraglottic and subraglottic region, cervical lymph node metastasis is significantly higher. Therefore, the area of tumor invasion is an important factor for lymph node metastasis.
- laryngeal neoplasm /
- cervical lymph node /
- related factors

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