突发性聋患者气导短纯音诱发的眼肌前庭诱发肌源性电位

王佩杰; 罗伟; 吴麟; 陈震宇; 陆小燕

doi:10.13201/j.issn.1001-1781.2015.14.003

突发性聋患者气导短纯音诱发的眼肌前庭诱发肌源性电位

- 1 安徽医科大学解放军八一临床学院(南京, 210002);
- 2 解放军第八一医院耳鼻咽喉头颈外科
基金项目:
南京军区十二五科研基金课题MS057资助(No:2011FZ0035)

详细信息

通讯作者: 罗伟,E-mail:conchlw@163.com

中图分类号: R764.43

收稿日期: 2015-03-31

Air-conducted ocular vestibular-evoked myogenic potential in patients with sudden sensorineural hearing loss

- 1 Department of Otorhinolaryngology, 81st Clinical Academy of PLA, Affliliated to Anhui Medical University, Nanjing, 210002, China;
- 2 Department of Otorhinolaryngology Head and Neck Surgery, 81st Hospital of PLA

More Information

Corresponding author: LUO Wei, E-mail: conchlw@163.com

Received Date: 31 March 2015

摘要

摘要: 目的:研究突发性聋患者的眼肌前庭诱发肌源性电位(oVEMP),了解突发性聋患者前庭系统受损范围及程度。方法:选择2013-12-2014-12期间35例诊断为单侧突发性聋的患者。进行气导短纯音诱发的oVEMP检测,计算P1和N1的潜伏期,P1~N1波间期及P1~N1复合波振幅,分别以单侧突发性聋患者的相对健康耳及55例(110耳)健康人对照,分析突发性聋患者椭圆囊及前庭上神经的功能。结果:35例突发性聋患者中,31例双耳均引出oVEMP图形,4例患耳未引出oVEMP图形,患耳引出率88%,95 dBHL气导短纯音刺激下31患耳获得P1的潜伏期(12.16±0.76)ms;N1的潜伏期(16.94±2.57)ms,P1~N1波间期(5.16±0.73)ms,P1~N1复合波振幅(2.89±1.66)μv。95 dBHL气导短纯音刺激下35健耳获得P1的潜伏期(11.92±0.85)ms;N1的潜伏期(17.07±1.04)ms,P1~N1波间期(5.15±0.69)ms,P1~N1复合波振幅(5.44±2.53)μv;55例健康人均引出典型的oVEMP波形,95 dBHL气导短纯音刺激下获得P1的潜伏期(11.53±0.80)ms;N1的潜伏期(16.61±0.87)ms,P1~N1波间期(5.18±1.04)ms,P1~N1复合波振幅(5.96±2.59)μv。突发性聋组患耳、对侧健耳、健康对照组分别进行比较,P1和N1的潜伏期,P1~N1波间期在各组间差异无统计学意义(P>0.05)。P1~N1复合波振幅突发性聋组患耳明显低于对侧健耳及健康人,差异有统计学意义(P<0.05)。结论:通过oVEMP检测突发性聋患者,可观察到P1~N1复合波振幅降低,可能与椭圆囊及前庭上神经的损害有关。
- ocular vestibular evoked myogenic potential /
- utricle /
- saccule /
- sudden sensorineural hearing loss
Abstract: Objective: To investigate the characteristics of air-conducted ocular vestibular-evoked myogenic potential(oVEMP) in patients with sudden sensorineural hearing loss(SSHL).So as to understanding the range and the degree of the vestibular system damage in patients with SSHL.Method: Thirty-five cases of unilateral SSHL were enrolled as the observing group from December in 2013 to December in 2014.500 Hz air-conducted tone burst was employed as stimulation.Fifity-five healthy young subjects were recruited as the control group.The results were compared between the affected ears, the contralateral ears and the normal controls.Result: Thirty-five patients with SSHL, 31 of them in both ears lead to oVEMP Waveform, 4 sick ears did not elicit oVEMP waveform, extraction rate of 88%.95 dBHL air-conducted get the latencies of P1 and N1,P1-N1 interval,peak-to-peak P1-N1 amplitude in healthy ear were (11.92±0.85)ms;(17.07±1.04)ms,(5.15±0.69)ms,(5.44±2.53)μv.95 dBHL air-conducted get the latencies of P1 and N1,P1-N1 interval,peak-to-peak P1-N1 amplitude in sick ear were (12.16±0.76) ms;(16.94±2.57)ms,(5.16±0.73)ms,(2.89±1.66)μv.The 55 cases (110 ears) were elicited P1-N1 complex typical, extraction rate was 100%.The threshold of oVEMP examination was(82.23±2.92) dBHL,95 dBHL air-conducted get the latencies of P1 and N1,P1-N1 interval,peak-to-peak P1-N1 amplitude in these healthy young people were(11.53±0.80)ms,(16.61±0.87)ms,(5.18±1.04)ms,(5.96±2.59)μv,there were no significant differences between the affected ears, the contralateral ears and the normal controls in the latencies P1 and N1,P1-N1 interval. The wave amplitude in SSHL were lower than the healthy ear and the healthy control group.Conclusion: Through the detection of oVEMP in patients with SSHL,we observed that P1-N1 wave amplitude decreased, and it may be related to the damage of the utricle and vestibular nerve.
- ocular vestibular evoked myogenic potential /
- utricle /
- saccule /
- sudden sensorineural hearing loss

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