鼻咽癌的生物靶向治疗进展

李燕巍, 谢广茹, 潘战宇. 鼻咽癌的生物靶向治疗进展[J]. 临床耳鼻咽喉头颈外科杂志, 2015, 29(7): 671-673. doi: 10.13201/j.issn.1001-1781.2015.07.029
引用本文: 李燕巍, 谢广茹, 潘战宇. 鼻咽癌的生物靶向治疗进展[J]. 临床耳鼻咽喉头颈外科杂志, 2015, 29(7): 671-673. doi: 10.13201/j.issn.1001-1781.2015.07.029
LI Yanwei, XIE Guangru, PAN Zhanyu. Advancement biological target therapy of nasopharyngeal carcinoma[J]. J Clin Otorhinolaryngol Head Neck Surg, 2015, 29(7): 671-673. doi: 10.13201/j.issn.1001-1781.2015.07.029
Citation: LI Yanwei, XIE Guangru, PAN Zhanyu. Advancement biological target therapy of nasopharyngeal carcinoma[J]. J Clin Otorhinolaryngol Head Neck Surg, 2015, 29(7): 671-673. doi: 10.13201/j.issn.1001-1781.2015.07.029

鼻咽癌的生物靶向治疗进展

详细信息
    通讯作者: 李燕巍,E-mail:liyanwei127@hotmail.com
  • 中图分类号: R739.63

Advancement biological target therapy of nasopharyngeal carcinoma

More Information
  • 加载中
  • [1]

    FORASTIERE A,KOCH W,TROTTI A,et al.Head and neck cancer[J].N Engl J Med,2001,345:1890-1900.

    [2]

    孙燕,石远凯.临床肿瘤内科手册[M].北京:人民卫生出版社,2009:718-719.

    [3]

    COHEN E E,LINGEN M W,VOKES E E.The expanding role of systemic therapy in head and neck cancer[J].J Clin Oncol,2004,22:1743-1752.

    [4]

    GIUSTI R M,COHEN M H,KEEGAN P,et al.FDA review of a panitu-mumab(Vectibix)clinical trial for first-line treatment of metastatic colorectal cancer[J].Oncologist,2009,14:284-290.

    [5]

    STEWART J S,COHEN E E,LICITRA L,et al.PhaseⅢstudy of gefitinib compared with intravenous methotrexate for recurrent squamous cell carcinoma of the head and neck[J].J Clin Oncol,2009,27:1864-1871.

    [6]

    LI G,XIE L,ZHOU G,et al.A clinical trial of active immunotherapy with anti-idiotypic vaccine in nasopharyngeal carcinoma patients[J].Chin Med J(Engl),2002,115:567-570.

    [7]

    BIAGI E,DOTTI G,YVON E,et al.Molecular transfer of CD40 and OX40 ligands to leukemichuman B cells induces expansion of autologous tumor-reactive cytotoxic T lymphocytes[J].Blood,2005,105:2436-2442.

    [8]

    GROTHEY A,SOBRERO A F,SIENA S.Results of a phaseⅢrandomized,double-blind,placebo-controlled,multicenter trial(CORRECT)of regorafenib plus best supportive care(BSC)versus placebo plus BSC in patients(pts)with metastatic colorectal cancer(mCRC)who have progressed after standard therapies[abstract].J Clin Oncol,2012,30(Suppl 4):LBA385.

    [9]

    CHUA D T,NICHOLLS J M,SHAM J S.Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy[J].In J Radiat Oncol Biol Phys,2004,59:11-20.

    [10]

    CHAN A T,HSU M M,GOH B C.Multicenter,phaseⅡstudy of cetuximab in combination with carboplatin in patients with recurrent ormetastatic nasopharyngeal carcinoma[J].J Clin Oncol,2005,23:3568-3576.

    [11]

    MA B B,KAM M K,LEUNG S F et al.A phaseⅡstudy of concur-rent cetuximab-cisplatin and intensitymodulated radiotherapy in locoregionally advanced nasopharyngeal carcinoma[J].Ann Oncol,2012,23:1287-1292.

    [12]

    MENG J,GU Q P,MENG Q F,et al.Efficacy of nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in treatment of advanced oral carcinoma[J].Cell Biochem Biophys,2014,68:181-184.

    [13]

    郭兵.帕尼单抗联合化疗治疗晚期头颈部肿瘤的研究[J].临床和实验医学杂志,2013,12(22):1811-1814.

    [14]

    KRISHNA S M,JAMES S,BALARAM P.Expression of VEGF as prognostic-cator in primary nasopharyngeal cancer and its relation to EBV status[J].Virus Res,2006,115:85-90.

    [15]

    LEE N Y,ZHANG Q,PFISTER D G.Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma(RTOG0615):aphase 2 multi-institutional trial[J].Lancet Oncol,2012,13:172-180.

    [16]

    YOO D S,KIRKPATRICK J P,CRACIUNESCU O,et al.Prospective trial of synchronous bevacizumab,erlotinib,and concurrent chemoradiation in locally advanced head and neck cancer[J].Clin Cancer Res,2012,18:1404-1414.

    [17]

    HAINSWORTH J D,SPIGEL D R,GRECO F A.Combined modality treatment with chemotherapy,radiation therapy,bevacizumab,and erlotinib in patients with locally advanced squamous carcinoma of the head and neck:aphaseⅡtrial of the Sarah Cannon oncology researchi consortium[J].Cancer J,2011,17:267-272.

    [18]

    顾康生,吴秋良,侯景辉.HER-2/neu基因在鼻咽癌中的表达及其临床意义[J].癌症,2001,20(8):869-872.

    [19]

    DUNGO R T,KEATING G M.Afatinib:first global approval[J].Drugs,2013,73:1503-1515.

    [20]

    COHEN E E,KANE M A,LIST M A,et al.PhaseⅡtrial of gefitinib 250 mg daily in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck[J].Clin Cancer Res,2005,11:8418-8424.

    [21]

    SOULIERES D,SENZER N N,VOKES E E.Multicenter phaseⅡstudy of erlotinib,an oral epidermal growth factor receptor tyrosine kinase inhibitor,in patients with recurrent or metastatic squamous cell cancer of the head and neck[J].J Clin Oncol,2004,22:77-85.

    [22]

    刘媛,刘东伯,龙国贤,等.吉非替尼和依维莫司对EGFR-TKI耐药鼻咽癌细胞的作用[J].医药导报,2014,33(1):43-48.

    [23]

    陈楠,张红雨,彭培建,等.顺铂联合吉非替尼对鼻咽癌细胞生长抑制及其机制的探讨[J].中华肿瘤防治杂志,2011,18(8):575-579.

    [24]

    梁中敏,姚岐,刘维奇,李青.鼻咽癌组织中血管内皮生长因子和生存素的表达[J].中国基层医药,2010,17(11):1480-1482.

    [25]

    YAN G R,TAN Z,WANG Y.Quantitative proteomics characterization on the antitumor effects of isodeoxyelephantopin against nasopharyngeal carcinoma[J].Proteomics,2013,13:3222-3232.

    [26]

    LIU M,WANG W,LI X,et al.Wedelia chinensis inhibits nasopharyngeal carcinoma CNE-1cell growth by inducing G2/M arrest in a Chk1-dependent pathway[J].Am J Chin Med,2013,41:1153-1168.

  • 加载中
计量
  • 文章访问数:  41
  • PDF下载数:  16
  • 施引文献:  0
出版历程
收稿日期:  2014-12-23

目录