阻塞性睡眠呼吸暂停低通气综合征与支气管哮喘关系的研究进展

王金凤; 谢宇平; 马薇; 侯一平; 惠培林; 赵丽君; 魏晓泉

doi:10.13201/j.issn.1001-1781.2015.04.027

阻塞性睡眠呼吸暂停低通气综合征与支气管哮喘关系的研究进展

- 1. 甘肃省人民医院睡眠医学中心(兰州, 730000);
- 2. 兰州大学基础医学院

详细信息

通讯作者: 谢宇平,E-mail:xyp5894@163.com

中图分类号: R563.8

收稿日期: 2014-09-28

The research progress of relationship between the obstructive sleep apnea hypopnea syndrome and asthma

More Information

Corresponding author: XIE Yuping, E-mail: xyp5894@163.com

Received Date: 28 September 2014

摘要

- 睡眠呼吸暂停低通气综合征 /
- 阻塞性 /
- 哮喘 /
- 持续气道正压通气
Abstract: Obstructive sleep apnea hypopnea syndrome(OSAHS)is characterized by repeated episodes of upper airway obstruction that results in brief periods of breathing cessation(apnea)or a marked reduction in airflow(hypopnea)during sleep.Asthma is a chronic inflammatory disease of the airways characterized by revesible airflow obstruction and bronchial hyperresponsiveness.This article reviewed related reseaches progress of relationship between the obstructive sleep apnea hypopnea syndrom and asthma in the vascular endothelial growth factor,systemic inflammation,leptin,obesity,gastroesophageal reflux disease and upper airway diseases,excessive daytime sleepiness and asthma control.
- sleep apnea hypopnea syndrome /
- obstructive /
- asthma /
- continuous positive airway pressure

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参考文献(41)

[1]	GUVEN S F,DURSUN A B,CIFTCI B,et al.The prevalence of obstructive sleep apnea in patients with difficult-to-treat asthma[J].Asian Pac J Allergy Immunol,2014,32:153-159.
[2]	BYUN M K,PARK S C,CHANG Y S,et al.Associations of moderate to severe asthma with obstructive sleep apnea[J].Yonsei Med J,2013,54:942-948.
[3]	LI J,LI C,CHAI L,et al.Relationship between plasma vascular endothelial growth factor and tumor necrosis factor-alpha and obstructive sleep apnea hypopnea syndrome in children[J].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi,2014,49:44-48.
[4]	CIFTCI T U,KOKTURK O,DEMIRTAS S,et al.Consequences of hypoxia-reoxygenation phenomena in patients with obstructive sleep apnea syndrome[J].Ann Saudi Med,2011,31:14-18.
[5]	LAVIE L,KRAICZI H,HEFETZ A,et al.Plasma vascular endothelial growth factor in sleep apnea syndrome:effects of nasal continuous positive air pressure treatment[J].Am J Respir Crit Care Med,2002,165:1624-1628.
[6]	HARKNESS L M,KANABAR V,SHARMA H S,et al.Pulmonary vascular changes in asthma and COPD[J].Pulm Pharmacol Ther,2014,29:144-155.
[7]	HOSHINO M,TANAKA H,ABE S.Quantitative analysis of bronchial wall vascularity in the medium and small airways of patients with asthma and COPD[J].Chest,2005,127:965-972.
[8]	SOOSE R J.Role of allergy in sleep-disordered breathing[J].Otolaryngol Clin North Am,2011,44:625-635.
[9]	KHEIRANDISH-GOZAL L,PERIS E,WANG Y,et al.Lipopolysaccharide-binding protein plasma levels in children:effects of obstructive sleep apnea and obesity[J].J Clin Endocrinol Metab,2014,99:656-663.
[10]	BAESSLER A,NADEEM R,HARVEY M,et al.Treatment for sleep apnea by continuous positive airway pressure improves levels of inflammatory markers-a meta-analysis[J].J Inflamm(Lond),2013,10:13-13.
[11]	VGONTZAS A N,ZOUMAKIS E,BIXLER E O,et al.Selective effects of CPAP on sleep apnoea-associated manifestations[J].Eur J Clin Invest,2008,38:585-595.
[12]	GOZAL D,SERPERO L D,KHEIRANDISHGOZAL L,et al.Sleep measures and morning plasma TNF-alpha levels in children with sleep-disordered breathing[J].Sleep,2010,33:319-325.
[13]	SÁNCHEZ-DE-LA-TORRE M,MEDIANO O,et al.The influence of obesity and obstructive sleep apnea on metabolic hormones[J].Sleep Breath,2012,16:649-656.
[14]	CHEN Y C,DONG G H,LIN K C,et al.Gender difference of childhood overweight and obesity in predicting the risk of incident asthma:a systematic review and meta-analysis[J].Obes Rev,2013,14:222-231.
[15]	GULER N,KIRERLERI E,ONES U,et al.Leptin:does it have any role in childhood asthma[J]?J Allergy Clin Immunol,2004,114:254-259.
[16]	ALKHALIL M,SCHULMAN E,GETSY J.Obstructive sleep apnea syndrome and asthma:what are the links[J]?J Clin Sleep Med,2009,5:71-78.
[17]	COTTRELL L,NEAL W A,ICE C,et al.Piedimonte G.Metabolic abnormalities in children withasthma[J].Am J Respir Crit Care Med,2011,183:441-448.
[18]	HOLGUIN F,ROJAS M,BROWN L A,et al.Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls[J].J Asthma,2011,48:217-223.
[19]	ALKHALIL M,SCHULMAN E,GETSY J.Obstructive sleep apnea syndrome and asthma:what are the links[J]?J Clin Sleep Med,2009,5:71-78.
[20]	SAMELSON C F.Gastroesophageal reflux and obstructive sleep apnea[J].Sleep,1989,12:475-476.
[21]	GUDA N,PARTINGTON S,VAKIL N.Symptomatic gastro-oesophageal reflux,arousals and sleep quality in patients undergoing polysomnography for possible obstructive sleep apnoea[J].Aliment Pharmacol Ther,2004,20:1153-1159.
[22]	ISHIZUKA T,HISADA T,KAMIDE Y,et al.The effects of concomitant GERD,dyspepsia,and rhinosinusitis on asthma symptoms and FeNO in asthmatic patients taking controller medications[J].J Asthma Allergy,2014,5:131-139.
[23]	SONTAG S J,O'CONNELL S,KHANDELWAL S,et al.Asthmatics with gastroesophageal reflux:long term results of a randomized trial of medical and surgical antireflux therapies[J].Am J Gastroenterol,2003,98:987-999.
[24]	COUSSENS S,BAUMERT M,KOHLER M,et al.Movement distribution:a new measure of sleep fragmentation in children with upper airway obstruction[J].Sleep,2014,37:2025-2034.
[25]	DONNELLY L F,CASPER K A,CHEN B.Correlation on cine MR imaging of size of adenoid and palatine tonsils with degree of upper airway motion in asymptomatic sedated children[J].AJR Am J Roentgenol,2002,179:503-508.
[26]	KHEIRANDISH-GOZAL L,GOZAL D.Intranasal budesonide treatment for children with mild obstructive sleep apnea syndrome[J].Pediatrics,2008,122:e149-155.
[27]	CRUZ A A.The 'united airways' require an holistic approach to management[J].Allergy,2005,60:871-874.
[28]	LAVIGNE F,PETROF B J,JOHNSON J R,et al.Effect of topical corticosteroids on allergic airway inflammation and disease severity in obstructive sleep apnoea[J].Clin Exp Allergy,2013,43:1124-1133.
[29]	CALHOUN S L,VGONTZAS A N,FERNANDEZMENDOZA J,et al.Prevalence and risk factors of excessive daytime sleepiness in a community sample of young children:the role of obesity,asthma,anxiety/depression,and sleep[J].Sleep,2011,34:503-507.
[30]	EKICI A,EKICI M,KURTIPEK E,et al.Association of asthma-related symptoms with snoring and apnea and effect on health-related quality of life[J].Chest,2005,128:3358-3363.
[31]	CHUGH I M,KHANNA P,SHAH A.Nocturnal symptoms and sleep disturbances in clinically stable asthmatic children[J].Asian Pac J Allergy Immunol,2006,24:135-142.
[32]	KOINIS-MITCHELL D,CRAIG T,ESTEBAN C A,et al.Sleep and allergic disease:a summary of the literature and future directions for research[J].J Allergy Clin Immunol,2012,130:1275-1281.
[33]	TEODORESCU M,POLOMIS D A,HALL S V,et al.Association of obstructive sleep apnea risk with asthma control in adults[J].Chest,2010,138:543-550.
[34]	BULCUN E,EKICI M,EKICI A,et al.Bronchial hyperresponsiveness in patients with obstructive sleep apnea syndrome[J].Tuberk Toraks,2013,61:221-226.
[35]	KHEIRANDISH-GOZAL L,DAYYAT E A,EID N S,et al.Obstructive sleep apnea in poorly controlled asthmatic children:effect of adenotonsillectomy[J].Pediatr Pulmonol,2011,46:913-918.
[36]	GUTIERREZ M J,ZHU J,RODRIGUEZ-MARTINEZ C E,et al.Nocturnal phenotypical features of obstructive sleep apnea(OSA)in asthmatic children[J].Pediatr Pulmonol,2013,48:592-600.
[37]	JULIEN J Y,MARTIN J G,ERNST P,et al.Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma[J].J Allergy Clin Immunol,2009,124:371-376.
[38]	PRASAD B,NYENHUIS S M,WEAVER T E.Obstructive sleep apnea and asthma:associations and treatment implications.Sleep[J].Med Rev,2014,18:165-171.
[39]	SUNDAR K M,DALY S E,WILLIS A M.A longitudinal study of CPAP therapy for patients with chronic cough and obstructive sleep apnoea[J].Cough,2013,9:19-19.
[40]	TEODORESCU M,CONSENS F B,BRIA W F,et al.Predictors of habitual snoring and obstructive sleep apnea risk in patients with asthma[J].Chest,2009,135:1125-1132.
[41]	GUVEN S F,DURSUN A B,CIFTCI B,et al.The prevalence of obstructive sleep apnea in patients with difficult-to-treat asthma[J].Asian Pac J Allergy Immunol,2014,32:153-159.