变应性鼻炎特异性舌下免疫治疗

程雷

doi:10.13201/j.issn.1001-1781.2015.03.001

变应性鼻炎特异性舌下免疫治疗

程雷^,

- 南京医科大学第一附属医院江苏省人民医院耳鼻咽喉科(南京, 210029)
基金项目:
江苏高校优势学科建设工程(No:JX10231801)

江苏省科教兴卫工程医学重点人才(No:RC2011071)

详细信息

作者简介:
程雷,医学博士,教授,主任医师,博士研究生导师。现任南京医科大学第一附属医院(江苏省人民医院)耳鼻咽喉科主任,江苏省耳鼻咽喉科医疗质量控制中心主任,江苏省临床医学研究院过敏与自身免疫性疾病研究所副所长。主要学术职务有:中华医学会变态反应学分会委员,耳鼻咽喉头颈外科学分会委员,鼻科学组副组长;中国中西医结合学会耳鼻咽喉科专业委员会鼻炎鼻窦炎专家委员会副主任;江苏省医学会耳鼻咽喉科学分会主任委员,变态反应学分会候任主任委员;江苏省科技咨询专家。担任《中华耳鼻咽喉头颈外科杂志》和《中国中西医结合耳鼻咽喉科杂志》副总编,《临床耳鼻咽喉头颈外科杂志》、《中华临床免疫和变态反应杂志》等核心期刊编委。主攻研究方向为:鼻变态反应和炎症的分子机制。参与制定我国《慢性鼻-鼻窦炎诊断和治疗指南》、《变应性鼻炎诊断和治疗指南》、《儿童变应性鼻炎诊断和治疗指南》、《变应性鼻炎特异性免疫治疗专家共识》、《儿童鼻-鼻窦炎诊断和治疗建议》、《血管运动性鼻炎诊断和治疗建议》。"十一五"期间工作成绩突出,被授予"江苏省优秀重点人才"荣誉称号。

通讯作者: 程雷,E-mail:jspent@126.com

中图分类号: R765.21

收稿日期: 2015-01-16

Sublingual specific immunotherapy for allergic rhinitis

CHENG Lei^,

More Information

Corresponding author: CHENG Lei, E-mail: jspent@126.com

Received Date: 16 January 2015

摘要

- 鼻炎 /
- 变应性 /
- 投药 /
- 舌下 /
- 免疫治疗
- rhinitis /
- allergic /
- administration /
- sublingual /
- immunotherapy

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参考文献(16)

[1]	Allergen immunotherapy:therapeutic vaccines for allergic diseases. Geneva:January 27-291997[J]. Allergy, 1998,53(44 Suppl):1-42.
[2]	GORDON BR. The allergic march:can we prevent allergies and asthma[J]? Otolaryngol Clin North Am, 2011, 44:765-777.
[3]	CANONICA G W, COX L, PAWANKAR R, et al.Sublingual immunotherapy:World Allergy Organization position paper 2013 update[J]. World Allergy Organ J, 2014, 7:6-6.
[4]	程雷, 陈若希. 变应原特异性免疫治疗的现状与展望[J]. 中华耳鼻咽喉头颈外科杂志, 2011, 46(12):972-975.
[5]	陶绮蕾, 程雷. 儿童变应性鼻炎的特异性免疫治疗[J]. 中华耳鼻咽喉头颈外科杂志, 2012,47(8):694-698.
[6]	CALDERÓN M A, SIMONS F E, MALLING H J, et al. Sublingual allergen immunotherapy:mode of action and its relationship with the safety profile[J].Allergy, 2012, 67:302-311.
[7]	TIAN M, WANG Y, LU Y, et al. Effects of sublingual immunotherapy for Dermatophagoides farinae on Th17 cells and CD4⁺ CD25⁺ regulatory T cells in peripheral blood of children with allergic asthma[J]. Int Forum Allergy Rhinol, 2014, 4:371-375.
[8]	DI BONA D, PLAIA A, SCAFIDI V, et al. Efficacy of sublingual immunotherapy with grass allergens for seasonal allergic rhinitis:a systematic review and meta-analysis[J]. J Allergy Clin Immunol, 2010, 126:558-566.
[9]	RADULOVIC S, WILSON D, CALDERON M, et al. Systematic reviews of sublingual immunotherapy (SLIT)[J]. Allergy, 2011, 66:740-752.
[10]	WANG D H, CHEN L, CHENG L, et al. Fast onset of action of sublingual immunotherapy in house dust mite-induced allergic rhinitis:a multicenter, randomized, double-blind, placebo-controlled trial[J]. Laryngoscope, 2013, 123:1334-1340.
[11]	SHAO J, CUI Y X, ZHENG Y F, et al. Efficacy and safety of sublingual immunotherapy in children aged 3-13 years with allergic rhinitis[J]. Am J Rhinol Allergy, 2014, 28:131-139.
[12]	陈实, 王灵, 廖锋, 等. 舌下含服粉尘螨滴剂治疗学龄前与学龄期儿童过敏性哮喘伴变应性鼻炎的疗效评估[J]. 中华儿科杂志, 2013, 51(11):831-835.
[13]	朱亮, 陆纪红, 谢青, 等. 皮下免疫和舌下免疫治疗尘螨变应性鼻炎的安全性及依从性分析[J].中华耳鼻咽喉头颈外科杂志, 2010, 45(6):444-449.
[14]	陈伯亚, 龙自铭, 黄燕君, 等. 舌下含服粉尘螨滴剂治疗单一和多重过敏变应性鼻炎患者的临床疗效评估[J].中华耳鼻咽喉头颈外科杂志, 2013, 48(7):549-554.
[15]	LEE J E, CHOI Y S, KIM M S, et al. Efficacy of sublingual immunotherapy with house dust mite extract in polyallergen sensitized patients with allergic rhinitis[J].Ann Allergy Asthma Immunol, 2011,107:79-84.
[16]	KIM S H, SHIN S Y, LEE K H, et al. Long-term effects of specific allergen immunotherapy against house dust mites in polysensitized patients with allergic rhinitis[J].Allergy Asthma Immunol Res, 2014, 6:535-540.