Laryngo-tracheal flap to reconstruct the defect after resection of the hypopharyngeal carcinoma with cervical esophagus involvement
-
摘要: 目的:探讨利用喉-气管组织瓣重建颈段食管的方法。方法:下咽癌累及颈段食管患者11例中,肿瘤累及一侧梨状窝及颈段食管8例,累及双侧梨状窝、咽后壁及颈段食管3例。手术完整切除咽喉及颈段食管病变,同期行双侧颈清扫。对喉及气管环状结构能完整保留者(3/11),直接与口咽部及病变下端颈胸段食管吻合;对咽喉部分保留者(8/11),作胸大肌肌皮瓣与之对合重建颈段食管。术后行放化疗,随访1~5年。结果:术后1例咽瘘、1例乳糜瘘,经2周左右换药痊愈。11例患者术后均正常进食,无吻合口狭窄。6例患者术后随访3年无复发,4例放疗半年后颈部出现淋巴结转移,1例术后1年胸段食管癌伴肝转移未治失访。3年生存率为54.5%。结论:喉气管组织瓣重建下咽癌累及颈段食管切除术后颈段食管是一种制作过程简单、效果确实、术后并发症少的修复重建方法。Abstract: Objective:To investigate cervical esophageal reconstruction by means of laryngo-tracheal flap after resection of hypopharyngeal carcinoma with cervical esophageal involvement.Method:Eleven cases of hypopharyngeal carcinoma with cervical esophageal involvement. Unilateral piriform sinus and cervical esophagus were involved in 8 cases (8/11) while bilateral piriform sinus, posterior pharyngeal wall and cervical esophagus were involved in 3 cases. After resection of laryngeal, pharyngeal and esophageal tumors and bilateral neck dissection, direct anastomosis of larynx and trachea with esophagus of cervico-thoracic segment was performed if circular structure of larynx and trachea could be preserved (3/11), pectoralis major myocutaneous flap was employed if only part of pharynx and larynx could be preserved (8/11). Postoperative radiochemotherapy was adopted and follow-up lasted for 1-5 years. Result:All cases healed without event except for one case of pharyngeal fistula and one case of chylous fistula which also healed after about 2 weeks dressing change. All patients got normal diet without anastomotic stricture. There was no recurrence in 6 patients at the 3 years follow-up, 4 patients had metastases in the neck and 1 patient had thoracic esophageal carcinoma with hepatic metastasis and gave up further treatment. The overall 3-year survival rate was 54.5%. Conclusion:Using laryngo-tracheal flap to reconstruct cervical esophagus after resection of hypopharyngeal carcinoma with cervical esophageal involvement is a recommendable method that is simple in processing, reliable in effect and less in postoperative complications.
-
Key words:
- hypopharyngeal neoplasms /
- esophagus /
- reconstructive surgical procedures
-
-
[1] 唐平章, 张宗敏, 祁永发, 等.303例下咽癌的外科治疗及组织移植修复重建术的临床分析[J].中华耳鼻咽喉头颈外科杂志, 2004, 39 (3):166-170.
[2] OGURA J H, JUREMA A A, WATSON R K.Partial laryngopharyngectomy and neck dissection for pyriform sinus cancer.Conservation surgery with immediate reconstruction[J].Laryngoscope, 1960, 70:1399-1417.
[3] SAKURABA M, ASANO T, MIYAMOTO S, et al.Three-dimensional reconstruction of supraglottic structures after partial pharyngolaryngectomy for hypopharyngeal cancer[J].Jpn J Clin Oncol, 2008, 38:408-413.
[4] LEFEBVRE J L, ANDRY G, CHEVALIER D, et al.Laryngeal preservation with induction chemotherapy for hypopharyngeal squamous cell carcinoma:10-year results of EORTC trial 24891[J].Ann Oncol, 2012, 23:2708-2714.
[5] 王建宏, 祁永发, 唐平章, 等.梨状窝癌手术前后放疗与喉功能保全[J].中华耳鼻咽喉头颈外科杂志, 2005, 40 (7):528-532.
[6] 李文, 易雪莲, 杨柳, 等.累及声门旁间隙的梨状窝癌的喉功能保存手术[J].临床耳鼻咽喉头颈外科杂志, 2014, 28 (5):601-603.
[7] 鄢丹桂, 张彬, 李德志, 等.下咽后壁鳞状细胞癌患者喉功能保留及修复[J].中华耳鼻咽喉头颈外科杂志, 2014, 49 (7):548-552.
[8] 屠规益.喉癌下咽癌现代理论与临床[M].济南:山东科学技术出版社, 2002:86-89.
[9] TAI S K, CHANG S Y.Contralateral hemilaryngotracheal flap reconstruction of the hypopharynx in pyriform carcinoma resection[J].Laryngoscope, 1999, 109 (2Pt 1):221-225.
[10] CHU P Y, CHANG S Y.Reconstruction of circumferential pharyngoesophageal defects with laryngotracheal flap and pectoralis major myocutaneous flap[J].Head Neck, 2002, 24:933-939.
[11] KATZENELL U, YEHESKELI E, SEGAL S, et al.Hemilaryngeal flap for hypopharyngeal reconstruction in piriform sinus carcinoma[J].Acta Otolaryngol, 2007, 127:4-7.
[12] 徐伟, 吕正华, 杨哲, 等.149例下咽癌手术及术后放射治疗的预后分析[J].中华耳鼻咽喉头颈外科杂志, 2014, 49 (7):533-538.
[13] HRADA R, ISOBE K, WATANABE M, et al.The incidence and significance of retropharyngeal lymph node metastases in hypopharyngeal cancer[J].Jpn J Clin Oncol, 2012, 42:794-799.
[14] 黄志刚.下咽癌治疗中的喉功能保留策略[J].中华耳鼻咽喉头颈外科杂志, 2014, 49 (7):529-531.
-
计量
- 文章访问数: 304
- PDF下载数: 153
- 施引文献: 0