The relationship between obstructive sleep apnea hypopnea syndrome and adenoid size as well as tonsil size in Children
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摘要: 目的:探讨儿童OSAHS与腺样体、扁桃体大小的关系。方法:2008-06-2010-10期间在我科门诊和病房以PSG确诊的338例OSAHS 患儿为病例组,并根据阻塞性呼吸暂停指数(OAI)或AHI分为轻、中、重3个亚组,同时采用简单随机抽样方法,选择同期就诊的无上呼吸道阻塞症状的207例声带小结患儿为对照组。对2组患儿口咽部、电子鼻咽喉镜的检查结果,进行回顾性分析,探讨腺样体、扁桃体大小与儿童OSAHS的相关性。以SPSS 17.0软件对数据进行统计学分析。结果:病例组Ⅲ、Ⅳ度腺样体以及Ⅲ、Ⅳ度扁桃体的比例分别为89.7%、68.4%,明显高于对照组的30.9%、13.5%,差异有统计学意义(均P<0.01)。病例组中,Ⅳ度与Ⅲ度腺样体比较,Ⅳ度与Ⅲ度扁桃体比较,前者发生OSAHS的危险程度明显增高。腺样体、扁桃体分度的比例在病例组轻、中、重亚组中逐级递增(P<0.01)。采用张口压舌法与电子鼻咽喉镜检查,对多数病例组患儿扁桃体大小和咽腔狭窄的判断结果一致。但35例张口压舌法检查为Ⅰ、Ⅱ度的扁桃体,其中13例(37.1%)以电子鼻咽喉镜检查扁桃体为Ⅲ度。结论:腺样体肥大、扁桃体肥大是儿童OSAHS的危险因素,其中Ⅳ度腺样体和Ⅳ扁桃体的发病风险明显增高;腺样体、扁桃体大小与儿童OSAHS的病情严重程度呈正相关;电子鼻咽喉镜检查是儿童OSAHS病因诊断的重要检查手段,且有助于包埋型扁桃体大小的判断。
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关键词:
- 睡眠呼吸暂停低通气综合征 /
- 阻塞性 /
- 儿童 /
- 腺样体肥大 /
- 扁桃体肥大
Abstract: Objective:To investigate the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and adenoid size as well as tonsil size in Children.Method:A total of 545 patients, 338 OSAHS patients (treated group) diagnosed by PSG and 207 patients with vocal cord nodules but symptoms of upper airway obstruction (control group), were enrolled from inpatient and outpatient between June, 2008 and October, 2010. The oropharynx and electron-nasopharyngolaryngoscopy examination records of the two groups were retrospectively analyzed. The patients in the treated group were also divided into mild group, moderate group and severe group according to obstructive apnea index (OAI) or AHI. SPSS 17.0 was used for statistical analysis.Result:In the treated group, 89.7% had grade Ⅲ-Ⅳadenoid and 68.4% had grade Ⅲ-Ⅳ tonsil, compared with 30.9% (adenoid) and 13.5% (tonsil) in the control group. The significant differences were found (all P<0.01). The comparison between patients with different grades of adenoidal size and tonsil size in the treated group had indicated that patients with grade Ⅳ adenoid or grade Ⅳtonsil have a higher risk of OSAHS than patients with grade Ⅲ adenoid or grade Ⅲ tonsil. In the treated group, the ratio of patients with different severity of adenoid or tonsil had increased with the severity of OSAHS(P<0.01). This retrospective study had also found that most of the grading results from Electron-nasopharyngolaryngoscopy examination were consistent with that from oropharynx examination. 13 (37.1%) of 35 patients with gradeⅠorⅡtonsil diagnosed by Oropharynx examination were considered as grade Ⅲ by Electron-nasopharyngolaryngoscopy examination.Conclusion:Adenoidal hypertrophy and tonsil hypertrophy are the risk factors for OSAHS in children. The risk of OSAHS and the severity of OSAHS are positively associated with the severity of adenoid and tonsil. The electron-nasopharyngolaryngoscopy examination is an important examination method for diagnosing OSAHS in children, as well as determination of tonsil size.-
Key words:
- sleep apnea hypopnea syndrome /
- obstructive /
- children /
- adenoidal hypertrophy /
- tonsil hypertrophy
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[1] OLSON E J, MOORE W R, MORGENTHALER T I, et al.Obstructive sleep apnea hypopnea syndrome[J].Mayo Clin Proc, 2003, 78:1545-1552.
[2] GUILLEMINAULT C, LEE J H, CHAN A.Pediatric obstructive sleep apnea syndrome[J].Arch Pediatr Adolesc Med, 2005, 159:775-785.
[3] FABIANA C P, MELISSA A G, MARCIA B P, et al.OSAS in children:correlation between endoscopic and polysomnographic findings[J].Otolaryngol Head Neck Surg, 2005, 132:268-272.
[4] 蔡谦, 苏振忠, 文卫平, 等.儿童阻塞性睡眠呼吸暂停低通气综合征扁桃体腺样体评价[J].中国耳鼻咽喉头颈外科, 2006, 13 (7):437-440.
[5] 黄健聪, 叶进, 杨钦泰, 等.阻塞性睡眠呼吸暂停低通气综合征患儿临床指标与睡眠监测的相关性分析[J].临床耳鼻咽喉头颈外科杂志, 2009, 23 (18):837-839.
[6] 高帆, 谷庆隆.儿童阻塞性睡眠呼吸暂停低通气综合征[J].中华医学杂志, 2009, 89 (36):2586-2588.
[7] 中华耳鼻咽喉头颈外科杂志编委会, 中华医学会耳鼻咽喉科学分会.《儿童阻塞性睡眠呼吸暂停低通气综合征诊疗指南草案 (乌鲁木齐) 》[J].中华耳鼻咽喉头颈外科杂志, 2007, 42 (1):83-84.
[8] 沈晓明, 王卫平.儿科学[M].7版.北京:人民卫生出版社, 2008:261-262.
[9] LINER L H, MARCUS C L.Ventilatory management of sleep-disordered breathing in children[J].Curr Opin Pediatr, 2006, 18:272-276.
[10] LIU D B, QIU S Y, ZHONG J W, et al.Diagnosis and treatment of obstructive sleep apnea hypopnea syndrome in children with risk factors[J].Zhong Hua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2008, 43:924-928.
[11] XU Z, JIAQING A, YUCHUAN L, et al.A casecontrol study of obstructive sleep apnea-hypopnea syndrome in obese and nonobese chinese children[J].Chest, 2008, 133:684-689.
[12] 刘大波, 罗绍鹏, 周丽枫, 等.不同年龄组儿童阻塞性睡眠呼吸暂停综合征257例临床分析[J].中国实用儿科杂志, 2004, 19 (7):417-419.
[13] CASSANO P, GELARDI M, CSSSANO M, et at.Adenoid tissue rhinopharyngeal obstruction grading based on fiberendoscopie fingings:a novel approach to therapeutic management[J].Int J Pediatr Otorhinolaryngol, 2003, 67:1303-1309.
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