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摘要: 目的:探讨非鳞状细胞来源声门下区肿物的临床特征,诊断、病理类型和治疗方法,提高对这一罕见疾病的认识。方法:分析3例非鳞状细胞来源声门下区肿物患者的临床资料,结合相关文献,总结非鳞状细胞来源的声门下区肿物的临床表现、诊断和治疗经验。结果:3例患者中,1例以声嘶为主要症状,2例以吸气性呼吸困难为主要症状;3例在明确诊断及解除喉梗阻后均行声门下区肿物切除手术,其中2例经口行支撑喉镜下手术切除,1例经颈部入路切开环甲膜后行肿物切除手术,均完整切除肿物。1例上皮-肌上皮癌患者采取术后放疗,疗效满意。3例随访至今,无复发。结论:声门下型非鳞状细胞来源肿物较为罕见,早期容易漏诊,临床上应对声门下区仔细检查。治疗该类疾病以手术切除为主,可根据肿物大小、范围选择适宜的手术方式。Abstract: Objective:To study clinical characteristics, diagnosis, pathological types and therapy methods of nonsquamous cell neoplasm in subglottis, in order to improve comprehension of this rare disease.Method:To analysis 3 patients' clinical data with nonsquamous cell neoplasm in subglottis by reviewing related literature, and to generalize the symptoms, differentiation and treatment experience of nonsquamous cell neoplasm in subglottis.Result:Among the 3 patients, one's main complain was hoarseness and the other two's main symptom was inspiratory dyspnea. As diagnosis was definite and acute obstruction of airway was relived, the neoplasms were removed totally. Two patients were undergone operation through oral cavity by using suspended laryngoscope, and one patient was done surgery by neck approach. Paraffin wax result showed that one patient suffered epithelial-myoepithelial carcinoma, who received radiotherapy after surgery. There is no recurrence in all patients by following up more than 1 year.Conclusion:The occurrence of nonsquamous cell neoplasm in subglottis is relatively low, and the subglottis should be inspected carefully to avoid missed diagnosis. Operation is the preferred method to treat this kind of disease. To choose a suitable operational manner according to size, location of the neoplasm is crucial.
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Key words:
- nonsquamous cell /
- neoplasm in subglottis /
- symptom /
- therapy
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