听觉皮层诱发电位对语后聋人工耳蜗植入效果的评估

阚赪; 刘辉; 傅新星; 陈雪清; 王硕; 莫玲燕; 郑军; 李永新; 龚树生; 韩德民

doi:10.13201/j.issn.1001-1781.2013.19.013

听觉皮层诱发电位对语后聋人工耳蜗植入效果的评估

- 首都医科大学附属北京同仁医院北京市耳鼻咽喉科学研究所耳鼻咽喉头颈科学教育部重点实验室(首都医科大学)(北京, 100005)
基金项目:
北京市卫生系统高层次卫生技术人才培养基金 (No:2011-3-042

No:2009-3-29)

北京市自然科学基金面上项目 (No:7122034)

详细信息

通讯作者: 莫玲燕,E-mail:lingyanmo@gmail.com

中图分类号: R764.5

收稿日期: 2012-07-17

Cochlear implant performance evaluation with cortical auditory evoked potential in a group of post-lingually deaf adults

- Beijing Tong Ren Hospital, Capital Medical University Beijing Institute of Otolaryngology; Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University), Ministry of Education, Beijing, 100005, China

More Information

Corresponding author: MO Lingyan, E-mail: lingyanmo@gmail.com

Received Date: 17 July 2012

摘要

摘要: 目的:采用听觉皮层诱发电位(CAEP)的方法探讨人工耳蜗使用早期听觉中枢重塑的规律。目的:成人语后聋人工耳蜗植入者10例,术前双耳均为极重度感音神经性聋。术中电极全部植入。术后电极均可正常使用。分别于人工耳蜗开机后1、3及6个月进行P1-N1-P2以及言语测听的单音节词识别率测试。患者配戴人工耳蜗,在声场中测试,声强为60~70 dB SPL(以患者感觉舒适为准)。分别记录Fz电极P1-N1-P2及各波波幅、潜伏期以及单音节字识别率,并分析它们之间的关系。结果:术后6个月内,随着配戴人工耳蜗时间的增加,10例中的6例P1-N1-P2波形变得越来越典型,另4例在术后半年波形仍不典型,该组患者的共同特征是耳聋持续时间长、耳聋发病年龄早。人工耳蜗开机1、3以及6个月的P1、N1和P2波幅、潜伏期、P1-N1、N1-P2峰-峰波幅均无显著性差异,但单音节词识别率之间有显著性差异,单音节词识别率随时间而增加;P1-N1-P2各参数与单音节词识别率之间均无显著相关性。结论:耳聋持续时间和发病年龄会影响语后聋者P1-N1-P2的引出率和形态。该皮层反应的建立和完善需要至少半年以上的时间。
- 听觉皮层诱发电位 /
- 人工耳蜗植入
Abstract: Objective: To investigate the law of auditory remodeling by studying the Cortical Auditory Evoked Potential in a group of post-lingually deaf adults in the early stage of the cochlear implant use.Method: Ten post-lingually deaf adults implanted with PULSAR ci 100 of Medel device,ranged from 19 to 52 years old with duration of deafness from 3 months to 23 years,were involved. Their P1-N1-P2 responses to /bā/ at around 60-70 dB SPL and open-set speech recognition scores of mono-syllabic words were recorded at 1, 3 and 6 months after the switch-on of cochlear implants.Result: Six out of 10 typical waveforms of P1-N1-P2 were obtained. The other 4 were with atypical waveforms. The group with atypical waveform was characterized by long duration and early onset of deafness. There was no significant difference regarding either the amplitude or the latency of each peak at the 3 data collection time points. There was significant difference among the 3 data collection time points about the speech recognition scores with the highest score at the 6th month of switch on. There was no significant correlation between the peak of the CAEP and speech recognition score.Conclusion: In the first 6 months of cochlear implant use in the post-lingually deaf adults, the duration and the onset age of deafness played important role in respect of the presence and waveform morphology of the CAEPs. It needs at least 6 months for the central auditory system to make use of the audio input from the cochlear implant.
- cortical auditory evoked potential /
- cochlear implant

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参考文献(13)

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