喉癌喉全切除术后造瘘口复发癌相关因素的Meta分析

盛晓丽; 张思毅; 宋新汉; 陈良嗣; 罗小宁

doi:10.13201/j.issn.1001-1781.2013.18.008

喉癌喉全切除术后造瘘口复发癌相关因素的Meta分析

- 广东省人民医院耳鼻咽喉科广东省医学科学院(广州, 510080)

详细信息

通讯作者: 张思毅,E-mail:szhang555@hotmail.com

中图分类号: R739.65

收稿日期: 2012-11-26

Meta-analysis on the risk factors for stomal recurrence after total laryngectomy

- Department of Otolaryngology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou, 510080, China

More Information

Corresponding author: ZHANG Siyi, E-mail: szhang555@hotmail.com

Received Date: 26 November 2012

摘要

摘要: 目的:系统评价喉癌喉全切除术后造瘘口复发的部分危险因素。方法:国内文献来源以喉癌、喉全切除术或全喉切除术、复发为关键词检索万方数据库、中文学术期刊全文数据库、维普中文生物医学期刊数据库,国外文献来源以laryngectomy、stomal recurrence 为关键词检索Pubmed数据库、Embase数据库,手工检索所有纳入试验的参考文献,采用RevMan5.0软件对纳入文献的数据进行汇总分析(Meta分析)。结果:共纳入2篇中文文献,6篇英文文献,病例总数2 725例,造瘘口复发癌247例。全部入选病例造瘘口复发癌的发生率为9.06%。Meta分析结果显示原发于声门下区的肿瘤及跨声门型肿瘤、局部晚期的肿瘤(特别是T4)以及术前行气管切开术是喉全术后造瘘口复发的相关危险因素。结论:原发于声门下区的肿瘤及跨声门型肿瘤、局部晚期的肿瘤(T4)以及术前行气管切开术与喉癌喉全术后造瘘口复发有关。
- 喉肿瘤 /
- 喉全切除术 /
- 造瘘口复发 /
- 危险因素 /
- Meta分析
Abstract: Objective: To evaluate the risk factors of stomal recurrence in patients after total laryngectomy.Method: A thorough literature search was performed among Wanfang database, Chinese Scientific Journals Database of VIP and pubmed database.Meta analysis was performed on a total of 2 725 patients in 2 Chinese papers and 6 English papers which met the inclusion criteria. Data was analyzed by RevMan 5.0 software.Result: Subglottic and transglottic location(tumor location), the extent of the tumor of the primary site(T4), preoperative tracheotomy were important risk factors of recurrence after total laryngectomy.Conclusion: Subglottic and transglottic location(tumor location), the extent of the tumor of the primary site(T4), preoperative tracheotomy were related to stomal recurrence after total laryngectomy.
- laryngeal carcinoma /
- total laryngectomy /
- stomal recurrence /
- risk factors /
- Meta-analysis

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