Abstract: Objective: To compare the efficacy and safety of applications of GlideScope video laryngoscope(GSVL) and Macintosh direct laryngoscope(MDLS) during endotracheal intubation under general anesthesia of abdominalsnoring surgeries.Method: Forty patients ranged from American Society of Anesthesiologists Ⅰ to Ⅲ scheduled for snoring surgery under general anesthesia with endotracheal intubation were randomly divided into GSVL group and MDLS group(20 cases in each group), After traditional induction, endotracheal intubation(ETT) performed by GSVL or MDLS. Glottic exposure, the time of endotracheal intubation(from mask ventilation ending to successful intubation),the times of tracheal intubation operation were recorded in both groups.The mean artery pressure(MAP), heart rate(HR) were monitored before induction(basic value T0),before tracheal intubation(T1),after tracheal intubation(T2),1min after tracheal intubation(T3),3mins after tracheal intubation(T4).Result: The glottic exposure of GSVL group is superior to that of MDLS group. There was no significant difference in the time of tracheal intubation between MDLS group(27±11)s and GSVL group(26±11)s (P<0.05). Compared with T0,MAP of T1 was lower in two groups (P<0.05),while HR were similar both in two groups(P>0.05). MAP of T2 and T3 increased and HR became faster(P< 0.05). MAP of T4 declined, but HR still increased(P<0.05).Between the two groups, there was no significant difference of MAP or HR (P>0.05). Conclusion: Comparied with MDLS,the GSVL is of benefit to improve the glottic exposure in endotracheal intubation to the snoring patients,so as to improve the success rate of tracheal intubation.But there is no obvious advantages via GSVL in preventing hemodynamic reaction during tracheal intubation.